A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors.

Launched by CENTRE LEON BERARD · Dec 11, 2020

Keywords

ClinConnect Summary

This clinical trial is studying how to identify and manage health issues that may arise after cancer treatments in survivors. Many cancer survivors experience new health problems years after their treatment, which can lower their quality of life. The trial, called PASCA, involves patients who have been treated for specific types of cancer and are in complete remission. Participants will attend four check-up visits over five years, where they will be screened for 22 potential complications related to their cancer treatment. This includes questionnaires about their well-being and various medical tests to assess their overall health.

To be eligible for the study, participants must be between 18 and 65 years old, have completed chemotherapy for certain cancers, and be able to engage in physical activity. They should also live in the Auvergne-Rhône-Alpes region and be able to read and write in French. By taking part in this trial, patients may receive important follow-up care that could help improve their health and quality of life after cancer treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥ 18 years old and ≤ 65 years old.
• • 2. Follow-up at the Léon Bérard center
• 3. Treated by chemotherapy for one of the following pathologies, and confirmed by the reference diagnostic technique :
• • acute myeloid leukemia;
• • Hodgkin's lymphoma;
• • aggressive non-Hodgkin's lymphoma;
• • primary non-metastatic invasive breast carcinoma;
• • testicular germ cell tumor treated with at least 3 courses of BEP (bleomycin, etoposide, cisplatin), 4 courses of EP (etoposide, cisplatin) or 4 courses of VIP (etoposide, ifosfamide, cisplatin) received;
• • high-grade soft tissue sarcoma, osteosarcoma or Ewing's sarcoma.
• • 4. As a complete response at the end of treatment consultation. If end-of-treatment evaluation is not available at the time of inclusion: as an assumed complete response in the opinion of the investigator based on the previous assessment of response.
• • 5. Whose capacity to practice an adapted physical activity will have been certified by a medical certificate issued by the investigating physician, the general practitioner or the referring physician.
• • 6. Able to understand, read and write French.
• • 7. Available and willing to participate in the project throughout the duration of the study.
• • 8. Living in the Auvergne-Rhône-Alpes region or in the department of Saône-et-Loire
• • 9. Affiliated with a health insurance plan.
• • 10. Having declared an attending physician.
• • 11. Having signed and dated the informed consent.
• Exclusion Criteria:
• • 1. With a history of malignancy other than basal cell skin cancer.
• • 2. Cannot be followed for medical, social, family, geographical or psychological reasons for the duration of the study.
• • 3. Participating in other studies that could impact on the evaluation of the judgement criteria.
• • 4. Deprived of liberty by judicial or administrative decision.