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Search / Trial NCT04678609

OKV Versus CKC for Biomechanics and Function in Mild Knee OA Patients

Launched by UNIVERSITI SAINS MALAYSIA · Dec 16, 2020

Trial Information

Current as of July 21, 2025

Unknown status

Keywords

Biomechanics Exercise

ClinConnect Summary

The primary aim of this randomized controlled trial (RCT) is to compare the effects of two different home-based exercise programs namely OKC and CKC strengthening exercise intervention, on pain, disability, and quality of life on individuals with mild grade knee OA. Our secondary aim is to compare the effectiveness of OKC and CKC strengthening exercises on lower limb biomechanics during walking gait and sit to stand task. We hypothesize that after eight weeks of intervention OKC and CKC groups will show more improvements in pain, disability, and quality of life scores (what about the second...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • female patients
  • aged above 50
  • body mass index (BMI) \<30 kg / m2
  • diagnosed with grade I and II knee OA using Kellgren-Lawrence
  • have knee pain ≥ 2 on a VAS in the past week
  • Exclusion Criteria:
  • have neurological disorders
  • have implanted electrical devices
  • have non-ambulatory status
  • have significant cognitive impairment
  • presence of systemic inflammatory arthritis
  • have history of hip or knee arthroplasty
  • have history of trauma or surgical arthroscopy of either knee in the last 6 months
  • involved in a previous study that includes an exercise program within the last 6 months
  • received a knee intra-articular injection within the last 3 months
  • receives anticoagulant therapy
  • have recent or imminent surgery within the last 3 months
  • have any medical co-morbidities that excluding them from participation in exercises

About Universiti Sains Malaysia

Universiti Sains Malaysia (USM) is a leading research university in Malaysia, renowned for its commitment to advancing scientific knowledge and innovation in the healthcare sector. As a clinical trial sponsor, USM leverages its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous research aimed at improving patient outcomes and addressing pressing health challenges. The university fosters collaboration among researchers, medical professionals, and industry partners, ensuring that its clinical trials are conducted with the highest ethical standards and scientific integrity. Through its dedication to excellence in research and education, USM plays a pivotal role in shaping the future of healthcare both locally and globally.

Locations

Kota Bharu, Kelantan, Malaysia

Patients applied

0 patients applied

Trial Officials

Shazlin Shaharudin, PhD

Principal Investigator

Universiti Sains Malaysia

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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