Role of Pancreatic Exocrine Secretion in Weight Gain After Pancreas Transplantation

Launched by RUSH UNIVERSITY MEDICAL CENTER · Dec 29, 2020

Keywords

ClinConnect Summary

This clinical trial is looking at why some people gain a lot of weight after receiving a pancreas transplant. While pancreas transplants can help control blood sugar levels in patients with diabetes, many recipients experience significant weight gain, which can lead to other health issues like diabetes, heart disease, and increased risk of death. The researchers want to understand if the increased digestive juices from the new pancreas might be contributing to this weight gain. They believe that these juices help the body turn food into stored energy, leading to extra weight.

To participate in this study, you need to be between 18 and 80 years old and have received a pancreas transplant, either alone or along with other organs. Participants will undergo tests to measure certain digestive enzymes in their stool, which can help determine how their body is processing food. If the researchers confirm their theory, it could lead to new ways to manage weight gain after transplants, possibly using specific medications that target these digestive enzymes. If you're interested in learning more or considering participation, please talk to your healthcare provider.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Recipients of pancreas transplant with or without other organs
• • Age 18 - 80 yrs
• Exclusion Criteria:
• • Unwillingness to consent or participate in the study