Use of Laser Assisted New Attachment Procedure and Low Level Laser Therapy for Periodontitis Patients
Launched by IZMIR KATIP CELEBI UNIVERSITY · Jan 1, 2021
Trial Information
Current as of August 02, 2025
Completed
Keywords
ClinConnect Summary
The study was designed as a randomized-controlled, single-blind and parallel design consisting of 80 patients with chronic periodontitis. Study consists of 4 groups, with 20 patients in each group. Group 1 received only NSPT, Group 2 received NSPT+LANAP, Group 3 received NSPT+LLLT, and Group 4 received NSPT+LANAP+LLLT. Clinical measurements of patients and gingival crevicular fluid (GCF) were taken before treatment and after 1 and 3 months. In GCF, interleukin-1beta, interleukin-10 and vascular endothelial growth factor were analyzed. Standard periapical radiographs were taken for radiograp...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • periodontitis of periodontal stage II, III, or IV with grades B
- • with at least 12 teeth in the mouth and had ≥4 teeth but not all of them in the same quadrant
- • with Probing depth of ≥5 mm, Clinical attachment level of ≥4 mm
- • radiographic evidence of alveolar bone loss
- Exclusion Criteria:
- • smoking
- • pregnancy and lactation
- • using antibiotics in the last 6 months and anti-inflammatory drugs in the last 3rd months,
- • having the systemic disease and the use of the drug that will affect the periodontal condition, having restoration of the adjacent tooth to be collected gingival crevicular fluid
About Izmir Katip Celebi University
Izmir Katip Celebi University is a prominent academic institution in Turkey, dedicated to advancing medical research and education. The university is committed to fostering innovation and excellence in clinical trials, leveraging its state-of-the-art facilities and a multidisciplinary team of experienced researchers and healthcare professionals. With a focus on improving patient outcomes and contributing to the global body of medical knowledge, Izmir Katip Celebi University actively engages in collaborative research initiatives, aiming to address critical health challenges through rigorous scientific inquiry and ethical practices in clinical trial management.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Izmir, , Turkey
Patients applied
Trial Officials
Serhat Köseoğlu
Study Director
study manager
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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