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Search / Trial NCT04694222

Use of Laser Assisted New Attachment Procedure and Low Level Laser Therapy for Periodontitis Patients

Launched by IZMIR KATIP CELEBI UNIVERSITY · Jan 1, 2021

Trial Information

Current as of August 02, 2025

Completed

Keywords

Laser Assisted New Attachment Procedure Low Level Laser Therapy Periodontitis Non Surgical Periodontal Therapy

ClinConnect Summary

The study was designed as a randomized-controlled, single-blind and parallel design consisting of 80 patients with chronic periodontitis. Study consists of 4 groups, with 20 patients in each group. Group 1 received only NSPT, Group 2 received NSPT+LANAP, Group 3 received NSPT+LLLT, and Group 4 received NSPT+LANAP+LLLT. Clinical measurements of patients and gingival crevicular fluid (GCF) were taken before treatment and after 1 and 3 months. In GCF, interleukin-1beta, interleukin-10 and vascular endothelial growth factor were analyzed. Standard periapical radiographs were taken for radiograp...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • periodontitis of periodontal stage II, III, or IV with grades B
  • with at least 12 teeth in the mouth and had ≥4 teeth but not all of them in the same quadrant
  • with Probing depth of ≥5 mm, Clinical attachment level of ≥4 mm
  • radiographic evidence of alveolar bone loss
  • Exclusion Criteria:
  • smoking
  • pregnancy and lactation
  • using antibiotics in the last 6 months and anti-inflammatory drugs in the last 3rd months,
  • having the systemic disease and the use of the drug that will affect the periodontal condition, having restoration of the adjacent tooth to be collected gingival crevicular fluid

About Izmir Katip Celebi University

Izmir Katip Celebi University is a prominent academic institution in Turkey, dedicated to advancing medical research and education. The university is committed to fostering innovation and excellence in clinical trials, leveraging its state-of-the-art facilities and a multidisciplinary team of experienced researchers and healthcare professionals. With a focus on improving patient outcomes and contributing to the global body of medical knowledge, Izmir Katip Celebi University actively engages in collaborative research initiatives, aiming to address critical health challenges through rigorous scientific inquiry and ethical practices in clinical trial management.

Locations

Izmir, , Turkey

Patients applied

0 patients applied

Trial Officials

Serhat Köseoğlu

Study Director

study manager

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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