Remediation Program Via a "Serious Game" for the Cognitive Functions of Multiple Sclerosis Patients

Launched by LILLE CATHOLIC UNIVERSITY · Jan 4, 2021

Keywords

ClinConnect Summary

This clinical trial is looking at a new program designed to help improve thinking and memory skills in people with multiple sclerosis (MS) using a fun and engaging "serious game." The goal is to see if playing this game can help patients process information more quickly and learn better through their memories. The study is currently recruiting participants aged 18 to 65 who have been diagnosed with relapsing or progressive MS and have reported difficulties with cognitive functions, such as memory.

To participate, individuals should not have experienced a relapse in their MS for at least six weeks, should not be taking certain medications, and need to have access to the internet. Those who join the study can expect to engage with the game and participate in assessments to measure any changes in their cognitive abilities. It's important to note that individuals with severe cognitive issues or other specific health conditions may not be eligible to participate. This trial offers a unique opportunity to explore innovative ways to support cognitive health in MS patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Relapsing-remitting or progressive multiple sclerosis people defined according to Mc Donald's criteria revised in 2005
• • Age between ≥ 18 and ≤ 65 years old
• • Cognitive complaint, with at least one deficient score at the initial neuropsychological examination (\<5th percentile of the reference group), one of the scores of which concerns at least one BICAMS test
• • Have not had a definite relapse for at least 6 weeks
• • Be at least 4 weeks away from a corticosteroid bolus
• • Lack of neuroleptic treatment
• • Patient with an Internet connection
• • Signed informed consent
• Exclusion Criteria:
• • Severe cognitive deficit defined by obtaining a deficit score in more than six cognitive processes at the initial neuropsychological assessment.
• • Neuropsychological care
• • Inability to receive oral and written information
• • Inability to use the software (due in particular to motor and / or sensory difficulties),
• • Neurological or psychiatric comorbidity, other than MS and anxiodepressive syndrome
• • Patient with severe anxiodepressive syndrome (BDI\> 27)
• • Participation in an interventional study on cognitive functions
• • Patient under legal protection, guardianship or curatorship
• • Pregnant or breastfeeding women