Atrial Fibrillation in Active Cancer Patients

Launched by UNIVERSITY HOSPITAL, CAEN · Jan 4, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the relationship between atrial fibrillation (a heart rhythm issue) and active cancer in patients. Atrial fibrillation can happen in people with cancer, either due to the cancer itself or as a side effect of cancer treatments. Researchers want to learn more about how often serious heart problems occur in cancer patients who have experienced atrial fibrillation over a one-year period. To do this, they are creating a registry that will collect information from adult patients across multiple centers.

To participate in this trial, individuals need to be adults with an active cancer diagnosis (not including certain skin cancers or brain tumors) and have had at least one episode of atrial fibrillation after their cancer diagnosis. Patients who are currently receiving treatment for cancer or have had their cancer come back within the last six months may also qualify. Participants will be monitored for a year to track any major heart-related events. This study is important because it aims to fill gaps in understanding how cancer and atrial fibrillation impact each other, helping to improve care for patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • adult patients
• • outpatients or hospitalized patients
• • with a confirmed cancer (other than basal-cell or squamous-cell carcinoma of the skin, primary brain tumor, known intracerebral metastases, or acute leukemia) and an active cancer (defined as cancer that had been diagnosed within the past 6 months or recurrent locally advanced or metastatic cancer, for which anticancer treatment was being given at the time of enrollment or during 6 months before enrollment)
• • at least 1 episode of atrial fibrillation (new onset AF occuring after cancer diagnosis or history of paroxysmal of persistant AF prior to cancer diagnosis and an AF recurrence after cancer diagnosis)
• • in sinus rhythm at the time of cancer diagnosis
• Exclusion Criteria:
• • patient with palliative cares or other conditions resulting in short term death (death expected in the month following atrial fibrillation occurrence)
• • history of long-standing persistant or permanent AF prior to cancer diagnosis