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Search / Trial NCT04697849

Functional and Cognitive Rehabilitation of Hoarding Disorder

Launched by VA OFFICE OF RESEARCH AND DEVELOPMENT · Jan 5, 2021

Trial Information

Current as of July 26, 2025

Recruiting

Keywords

Hoarding Ocd Cognitive Rehabilitation Exposure Therapy

ClinConnect Summary

This clinical trial is studying a new approach to help Veterans with Hoarding Disorder (HD), a condition that can significantly affect their daily lives and overall well-being. The researchers aim to personalize a treatment called Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST) to make it more effective for each individual. In this study, 130 adult Veterans with HD will be randomly assigned to receive either the personalized treatment or standard case management. The goal is to see how this tailored approach can improve their quality of life and reduce the severity of their hoarding symptoms over 24 sessions.

To participate, Veterans must be 18 years or older and have a confirmed diagnosis of HD. They should also be stable on their medications for at least six weeks. Participants will receive care in the comfort of their own homes through telemedicine and home visits, making it easier to engage in the treatment. Throughout the study, the researchers will monitor various outcomes, including the participants' quality of life and their progress in recovery. This trial is an important step in understanding how to better support Veterans with Hoarding Disorder, ultimately helping them lead more fulfilling lives.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Veterans age 18 and older
  • voluntary informed consent for participation
  • DSM-5 diagnosis of HD as measured by the Structured Interview for Hoarding Disorder
  • HD as a primary diagnosis, and 5) stable on medications for at least 6 weeks
  • Exclusion Criteria:
  • current psychosis or mania as measured by the Mini-International Neuropsychiatric Interview
  • current or history of any neurodegenerative disease
  • concurrent participation in any form of exposure-based psychotherapy
  • suicide ideation will be monitored by the clinicians during sessions and VA standard suicide measure will be completed at all assessment points

About Va Office Of Research And Development

The VA Office of Research and Development (ORD) is dedicated to advancing the health and well-being of veterans through innovative research initiatives. As a pivotal sponsor of clinical trials, ORD focuses on a broad spectrum of health-related topics, including mental health, rehabilitation, and chronic disease management, ensuring that findings are directly applicable to the unique needs of the veteran population. With a commitment to scientific excellence and collaboration, ORD promotes rigorous study designs and ethical standards, facilitating the translation of research discoveries into improved clinical practices and policies that enhance veteran care.

Locations

San Diego, California, United States

San Diego, California, United States

Patients applied

0 patients applied

Trial Officials

Catherine R Ayers, PhD

Principal Investigator

VA San Diego Healthcare System, San Diego, CA

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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