Relationship of the Microenvironment and Male Fertility
Launched by UNIVERSITY OF ILLINOIS AT CHICAGO · Jan 7, 2021
Trial Information
Current as of November 01, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial, titled "Relationship of the Microenvironment and Male Fertility," is studying how the environment in semen (the fluid that carries sperm) and the gut might affect male fertility. Researchers want to find out if certain bacteria in these areas can influence the ability to conceive, especially in men who have been diagnosed with infertility after trying to conceive for a year without success. The study aims to identify new microorganisms in the semen that traditional testing might have missed, which could be linked to lower fertility.
Men who are diagnosed with infertility and agree to participate in the study may be eligible. However, those who have received hormone treatments, taken antibiotics in the past six months, or have identifiable reasons for infertility unrelated to hormone levels will not be included. Participants can expect to undergo semen analysis and blood tests to check hormone levels, and they may also provide samples for microbiome analysis, which looks at the types of bacteria present. This research could help improve understanding and treatment options for male infertility in the future.
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • Men diagnosed with infertility who consent to participate in the study
- Exclusion Criteria:
- • Prior hormone replacement therapy
- • Antibiotic use in past 6 months
- • Inability to consent for self, due to age or mental capacity
- • Infertility attributable to identifiable causes other than hypogonadism
About University Of Illinois At Chicago
The University of Illinois at Chicago (UIC) is a leading academic institution renowned for its commitment to advancing health sciences through innovative research and clinical trials. With a strong emphasis on interdisciplinary collaboration, UIC harnesses the expertise of its diverse faculty and state-of-the-art facilities to conduct cutting-edge clinical studies aimed at improving patient outcomes. The university's robust infrastructure for clinical research, combined with its dedication to ethical standards and regulatory compliance, positions UIC as a pivotal contributor to the development of new treatments and therapies in various medical fields. Through strategic partnerships and community engagement, UIC strives to translate research findings into real-world applications, enhancing the health and well-being of populations locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Chicago, Illinois, United States
Patients applied
Trial Officials
Samuel Ohlander, MD
Principal Investigator
University of Illinois at Chicago
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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