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Search / Trial NCT04707365

Microenvironment and Immunity of Digestive Cancers - East Paris Multicentric Cohort

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Jan 12, 2021

Trial Information

Current as of July 01, 2025

Not yet recruiting

Keywords

ClinConnect Summary

The clinical trial titled "Microenvironment and Immunity of Digestive Cancers - East Paris Multicentric Cohort" is focused on studying colorectal and pancreatobiliary cancers, which have become more common in recent years. Researchers want to understand how the environment around tumors and the body's immune system interact and influence the way these cancers grow and respond to treatment. The goal is to find new ways to diagnose and treat these cancers by looking at factors like the tumor's surroundings, the immune system, and even gut bacteria. This could help doctors predict how well a patient might do with certain treatments and what side effects they might experience.

To participate in this study, individuals must be at least 18 years old and have a confirmed diagnosis of colorectal or pancreatic adenocarcinoma (a type of cancer) or biliary tract adenocarcinoma, diagnosed since 2015. The study aims to include all eligible patients, regardless of their cancer stage or current treatment. Participants can expect to provide consent and have their medical information reviewed, contributing to important research that could lead to better treatment options for digestive cancers in the future. It's important to note that individuals who are pregnant, breastfeeding, or have certain legal or medical restrictions may not be able to participate.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Colorectal or pancreatic adenocarcinoma or biliary tract adenocarcinoma
  • Cytologically or histologically proven adenocarcinoma, regardless of stage and treatment
  • Age ≥ 18 years old
  • Diagnosed from 2015 onwards
  • Signed Consent
  • Affiliation to a social security scheme (including CMU (Universal health coverage))
  • Exclusion Criteria:
  • Patient under guardianship, curatorship or safeguarding of justice
  • Pregnant or breastfeeding woman
  • Any medical, psychological or social situation that could prevent compliance with the protocol according to the investigator's assessment.
  • Refusal to participate in the study
  • Patient on AME (state medical assistance)
  • Persons deprived of liberty by a judicial or administrative decision
  • Persons under psychiatric care

About Assistance Publique Hôpitaux De Paris

Assistance Publique - Hôpitaux de Paris (AP-HP) is a leading public hospital system in France, renowned for its commitment to healthcare excellence and innovative medical research. As a prominent clinical trial sponsor, AP-HP plays a pivotal role in advancing medical knowledge and improving patient care through rigorous scientific investigations across a wide range of therapeutic areas. With a focus on collaboration and interdisciplinary approaches, AP-HP leverages its extensive network of hospitals and expert clinicians to facilitate high-quality clinical trials that adhere to the highest ethical and regulatory standards, ultimately aiming to translate research findings into tangible health benefits for diverse patient populations.

Locations

Patients applied

0 patients applied

Trial Officials

Pr Tournigand

Study Director

AP-HP Henri Mondor Créteil

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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