Pathophysiology, Psycho-emotional and Cognitive Functioning Associated With Tinnitus

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Jan 15, 2021

Keywords

ClinConnect Summary

This clinical trial is studying tinnitus, a condition that causes ringing or buzzing in the ears, particularly in patients who have had surgery for drug-resistant temporal lobe epilepsy. Researchers want to understand how tinnitus affects cognitive abilities, emotions, and brain functions. They will compare patients with tinnitus—either those who have had surgery or those who have not—to groups of people who do not have tinnitus. This research aims to uncover new insights into what causes tinnitus and how it impacts daily life.

To participate, individuals must be at least 18 years old, understand French, and have normal or corrected vision. There are specific groups for participants: those experiencing chronic tinnitus for more than three months and those who have had surgery for epilepsy in the temporal lobe. Those without tinnitus or who have not had related surgery can also join. Participants can expect to undergo assessments that will help researchers learn more about the effects of tinnitus. It's important to note that people with severe hearing loss or certain medical conditions may not be eligible.

Gender

ALL

Eligibility criteria

• Common Criteria for Inclusion :
• • Age ≥ 18 years old
• • Good written and oral comprehension of the French language
• • Person affiliated to a Social Security scheme
• • Informed consent signed by the participant
• • Normal or corrected vision
• • Absence of known pre-existing neurological and/or degenerative disorders
• Group Specific Inclusion Criteria :
• • Tinnitus+ Group - Suffering from subjective uni- or bilateral tinnitus, chronic (\>3 months) and stable (no period of remission).
• • Chir+ Group
• • - Surgically treated for drug-resistant epilepsy of the temporal lobe (including the amygdala).
• • Group Tinnitus-
• • Not suffering from tinnitus Group Chir-
• • Non epileptic
• • Not having undergone surgical treatment of the temporal lobe (including the tonsil)
• Exclusion criteria:
• • Presence of severe or profound deafness, uni or bilateral.
• • Under legal protection (guardianship, curators, etc.)
• Additional criteria for patients completing visit V2 :
• • MRI contraindicated or claustrophobic
• • Pregnant or breastfeeding woman.