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Search / Trial NCT04726228

Pain ASsessment in CAncer Patients by Machine LEarning (PASCALE)

Launched by NATIONAL CANCER INSTITUTE, NAPLES · Jan 21, 2021

Trial Information

Current as of August 19, 2025

Recruiting

Keywords

Pain Assessment Machine Learning Automatic Pain Assessment Palliative Care Telemedicine Cancer Pain Quality Of Life

ClinConnect Summary

The PASCALE trial is studying how to better assess and manage pain in patients with advanced cancer using machine learning technology. The goal is to improve the quality of life for these patients by using telemedicine—essentially, healthcare delivered remotely through technology. This trial aims to develop better ways to measure pain, which is often very challenging in cancer patients. By gathering information from patients and healthcare providers, researchers hope to create systems that can automatically recognize and evaluate pain levels.

To participate in this study, patients must be over 18 years old, receiving home care for advanced cancer with a life expectancy of one year or less, and currently receiving treatment for cancer-related pain. They also need to be able to provide consent. Unfortunately, those under 18, unable to sign consent due to reading or writing difficulties, or with certain cognitive impairments are not eligible. If you join the trial, you can expect to share your experiences and help researchers develop new tools that could lead to better pain management for cancer patients in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients aged \> 18 years
  • Home care patients diagnosed with advanced cancer disease and life expectancy ≤ 1 year
  • Patients receiving treatment for cancer pain
  • Patients who have given their consent
  • Exclusion Criteria:
  • Patients aged \< 18 years
  • Willingness to sign the informed consent form (unable to read or write)
  • Cognitive deficit (e.g. Alzheimer disease or senile dementia)

About National Cancer Institute, Naples

The National Cancer Institute (NCI) in Naples is a leading research institution dedicated to advancing the understanding and treatment of cancer through innovative clinical trials. As a prominent sponsor of cancer research, the NCI focuses on developing novel therapies, improving patient outcomes, and exploring cutting-edge methodologies in oncology. With a commitment to scientific rigor and collaboration, the NCI in Naples engages in partnerships with academic institutions and healthcare providers to facilitate groundbreaking studies that address critical challenges in cancer care. Their mission is to translate research findings into effective treatments, ultimately enhancing the lives of patients affected by cancer.

Locations

Naples, Campania, Italy

Napoli, Campania, Italy

Patients applied

0 patients applied

Trial Officials

Marco Cascella, MD

Principal Investigator

Anesthesia and Pain Medicine. Istituto Nazionale Tumori - IRCCS Fondazione Pascale - Napoli, Italy

Arturo Cuomo, MD

Principal Investigator

Anesthesia and Pain Medicine. Istituto Nazionale Tumori - IRCCS Fondazione Pascale - Napoli, Italy

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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