Prevention of Perioperative Pulmonary Complications by Lung Recruitment During Laparoscopic Surgery
Launched by OSAKA UNIVERSITY · Jan 27, 2021
Trial Information
Current as of August 11, 2025
Unknown status
Keywords
ClinConnect Summary
The multi-center RCT will enroll 80 patients who have laparoscopic surgery in Trendelenburg head-down position. Informed consent will be obtained for study subjects who meet the selection criteria, and the subjects will be enrolled in Electronic Data Capture and randomized into two groups. Patients will be admitted to the operating room for induction of anesthesia and tracheal intubation. In the control group, mechanical ventilation will be performed according to the initial settings and protocols. In the intervention group, after intubation, the ventilator will be initially set up, and the...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients undergoing low head laparoscopic surgery who are expected to be laparoscopic for more than 2 hours
- Exclusion Criteria:
- • Lateral or supine position
- • BMI \> 35
- • One-second rate \<70%, %VC \<80%, obstructive, restrictive, with bra
- • Cardiovascular disease (NYHA III or higher)
- • Intracranial hypertensive disease
- • Emergency surgery
- • Pregnancy
- • Glaucoma
- • Patients judged unsuitable by the anesthesiologist in charge
About Osaka University
Osaka University is a prestigious research institution located in Japan, renowned for its commitment to advancing medical science and healthcare. As a clinical trial sponsor, Osaka University leverages its extensive academic resources and cutting-edge research capabilities to facilitate innovative studies that aim to improve patient outcomes and enhance therapeutic interventions. The university collaborates with leading experts in various fields, ensuring rigorous scientific methodologies and adherence to ethical standards in clinical research. Its dedication to translating research findings into clinical practice positions Osaka University as a pivotal player in the global healthcare landscape.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Suita, Osaka, Japan
Patients applied
Trial Officials
Yuji Fujino
Study Chair
Department of Anesthesiology and Intensive Care Medicine, Osaka University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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