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Search / Trial NCT04731857

Diagnostic Value of Exome/ Genome Sequencing, Conventional Methods in Rare Diseases and Familial Tumor Syndromes

Launched by UNIVERSITY HOSPITAL TUEBINGEN · Jan 26, 2021

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Rare Diseases Genetic Predisposition Next Generation Sequencing (Ngs) Polygenic Risk Scores (Pr Ss) Repeat Expansion Genetic Variation

ClinConnect Summary

This clinical trial is focused on understanding how effective advanced genetic tests, like exome and genome sequencing, are in diagnosing rare diseases and certain inherited tumor syndromes. The researchers are looking back at records from about 12,000 patients who had genetic tests done between October 2016 and December 2020. They want to see how these modern methods compare to traditional diagnostic techniques in identifying genetic conditions.

If you or a family member has a genetic disease and have undergone genetic testing during the specified period at the University Hospital Tübingen, you may be eligible to participate in this study. There are no strict age or gender requirements, and they welcome anyone with a genetic condition or their family members. Participants can expect to contribute to important research that could improve how these diseases are diagnosed in the future, helping doctors understand the best ways to use genetic testing.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patient with genetic disease or
  • Family members
  • Genetic analysis between 10/2016 and 12/2020 at the Institute for Medical Genetics and Applied Genomics at the University Hospital Tübingen
  • Exclusion Criteria:
  • - None

About University Hospital Tuebingen

University Hospital Tübingen is a leading academic medical institution in Germany, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital leverages its multidisciplinary expertise and cutting-edge facilities to develop new therapeutic strategies and improve patient outcomes. With a strong focus on translational medicine, University Hospital Tübingen collaborates with various stakeholders, including pharmaceutical companies and research organizations, to facilitate the efficient and ethical conduct of trials across a wide range of medical disciplines. Their dedication to patient-centered research and rigorous scientific standards positions them at the forefront of medical advancements.

Locations

Tübingen, , Germany

Patients applied

0 patients applied

Trial Officials

Tobias Haack, Dr.

Principal Investigator

University Hospital Tübingen

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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