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Search / Trial NCT04732052

The Use of Transcranial Direct Current Stimulation (tDCS) in Adults With Developmental Disabilities

Launched by DR. NAJAT KHALIFA · Jan 29, 2021

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called transcranial Direct Current Stimulation (tDCS) to help reduce aggressive behaviors in adults with developmental disabilities. Aggression can be a common challenge for people in this group, and researchers believe that tDCS, which is a non-invasive way to gently stimulate the brain, could help decrease impulsivity and aggression. The trial is currently looking for participants aged 18 to 64 who have a developmental disability and have shown aggressive behavior in the past month.

To take part in the study, individuals should not have a history of seizures, brain injuries, or certain medical devices like cochlear implants or pacemakers. Participants will receive the tDCS treatment and will be closely monitored to see how it affects their behavior. This trial aims to provide new insights into how we can better support individuals with developmental disabilities in managing aggression, ultimately improving their quality of life. If you're interested or have questions, please reach out to the research team for more information.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adults aged 18-64 years
  • Diagnosis of a developmental disability
  • History of one or more incidents of aggression in the last month
  • Consent to participate in the trial by the individual or their Substitute Decision Maker
  • Exclusion Criteria:
  • History of epilepsy or seizures
  • History of acquired brain injury
  • Having metal in the brain/skull, e.g. splinters, fragments or clips
  • Having a cochlear implant
  • Having an implanted neuro-stimulator (e.g. direct brain stimulation, epidural/subdural stimulation, vagal nerve stimulation)
  • History of brain surgery of procedure
  • History of severe adverse reaction to tDCS
  • Having a cardiac pacemaker or intracardiac lines
  • Current alcohol or drug misuse
  • Having a sensitive scalp

About Dr. Najat Khalifa

Dr. Najat Khalifa is a distinguished clinical trial sponsor with a strong commitment to advancing medical research and improving patient outcomes. With extensive expertise in clinical trial design and implementation, Dr. Khalifa leads initiatives that focus on innovative therapies and evidence-based practices. Her collaborative approach fosters partnerships among healthcare professionals, regulatory bodies, and research institutions, ensuring the highest standards of compliance and ethical conduct in all trials. Dr. Khalifa is dedicated to facilitating groundbreaking studies that contribute to the development of novel treatments and enhance the understanding of various medical conditions.

Locations

Kingston, Ontario, Canada

Kingston, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Muhammad Ayub, MD

Study Chair

Queen's University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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