An Exploratory Clinical Study on Autophagy During Fasting

Launched by CHARITE UNIVERSITY, BERLIN, GERMANY · Feb 1, 2021

Keywords

ClinConnect Summary

This clinical trial is exploring how fasting affects a process in our bodies called autophagy, which helps in cleaning out damaged cells and can contribute to improved health. Researchers want to understand how fasting influences autophagy in people with chronic conditions like rheumatoid arthritis and metabolic syndrome, compared to healthy individuals. By observing how autophagy works during fasting, the study aims to learn more about its role in health and disease.

To participate, you need to be between the ages of 65 and 74 and have either rheumatoid arthritis, metabolic syndrome, or be a healthy volunteer. Participants will be treated in the hospital for the first 24 hours and will need to provide written consent to join. This study is currently recruiting participants, and it’s important to note that people who have communication difficulties, cognitive disorders, are pregnant or breastfeeding, or are already part of another clinical trial cannot participate. If you join, you can expect to help researchers learn more about how fasting can impact health, which may lead to better treatments in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • One of the following diagnoses: rheumatoid arthritis, metabolic syndrome OR healthy volunteer
• • Beginning (first 24h) inpatient treatment or hospital stay at Immanuel Hospital Berlin, Department of Naturopathy OR healthy volunteer
• • Present written declaration of consent
• Exclusion Criteria:
• • Insufficient linguistic communication
• • Dementia or other cognitive disorder
• • Pregnancy or lactation
• • Simultaneous participation in another clinical trial