Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes

Launched by M.D. ANDERSON CANCER CENTER · Feb 3, 2021

Keywords

ClinConnect Summary

This clinical trial is studying how testosterone levels may be linked to dementia and mental health issues like anxiety and depression. Researchers want to find out if having low testosterone levels could increase the risk of developing dementia. Understanding this connection could help improve the quality of life for people undergoing certain medical treatments that lower testosterone levels, known as androgen deprivation therapy.

To participate in this study, you must be an adult who has volunteered to share your health information through national biobanks, such as the UK Biobank or Kaiser Permanente Research Bank. You should not be an adult who cannot give consent, someone who is not yet an adult, pregnant, or in prison. If you join the trial, you can expect to contribute to important research that may lead to better understanding and treatment options for mental health and dementia.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Have volunteered to participate in institutional or national biobanks, mainly the UK Biobank and the Kaiser Permanente Research Bank, and those that have previously participated in studies that resulted in de-identified clinical and genetic data being make available on public archives, mainly the database of Genotypes and Phenotypes (dbGaP)
• • No special populations (adults unable to consent, individuals not yet adults, pregnant women, or prisoners)