Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients

Launched by MEMORIAL SLOAN KETTERING CANCER CENTER · Feb 8, 2021

Keywords

ClinConnect Summary

This clinical trial is focused on creating new educational materials about genetic testing for cancer patients. Genetic testing looks for changes in your genes, which can help identify whether you have a genetic disorder or your chances of developing certain cancers. The study aims to make these materials accessible and understandable for people from different backgrounds, especially those who speak English, Haitian Creole, or Spanish. By interviewing participants and getting their feedback, the researchers hope to improve these educational resources to better serve patients with breast, ovarian, prostate, or pancreatic cancer.

To be eligible for this study, you should be at least 18 years old and have a current or past diagnosis of one of the specified cancers. Additionally, you should identify as Black, Latino, or neither, and be fluent in one of the target languages. Participants will review the educational materials and share their thoughts, which will help shape the final product. It's an opportunity to contribute to better resources for cancer patients and their families, making it easier for everyone to understand genetic testing and its implications for treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Phase 1
• • Age ≥ 18 years as per self-report
• • Current or previous diagnosis of breast, ovarian, pancreatic, or prostate cancer as per self-report
• • Self-identification as Black, Latino, and/or neither Black nor Latino (i.e.,non-Latino, Non black)
• • Fluency in English, Haitian Creole, or Spanish as per self-report (for Spanish, we will attempt to recruit a cohort representing a variety of regions where Spanish is spoken, as informed by current data from participating sites, to achieve neutrality in the language) Fluency is defined as an answer of "well" or "very well" on the screening questions for spoken and reading ability.
• Phase 2:
• • Age ≥ 18 years as per the medical record
• * Current or previous diagnosis of breast, colorectal, ovarian, pancreatic, or prostate cancer meeting at least one of the applicable criteria for the cancer type as per the medical record and/or clinician referral:
• * Breast cancer criteria:
• • any diagnosis age 65 or younger;
• • diagnosis of triple negative breast cancer at any age;
• • multiple primary breast cancers at any age;
• • under consideration for PARP therapy;
• • any family history (1st, 2nd, or 3rd degree relatives) of ovarian or pancreas cancer, or 1 relative with breast cancer who meets the above criteria, or 2 relatives with breast cancer at any age; or clinician discretion)
• * Colorectal cancer criteria:
• • any diagnosis age 50 and below;
• • mismatch repair deficient colorectal cancer;
• • colorectal cancer at any age with an additional Lynch syndromerelated primary cancer at any age;
• • colorectal cancer at any age with a 1st or 2nd degree relative with colorectal cancer at/before age 50;
• • colorectal cancer at any age with 2 or more 1st or 2nd degree relatives with a Lynch syndrome-related cancer at any age
• * Ovarian cancer criteria:
• • ° invasive ovarian cancer
• * Pancreatic cancer criteria:
• • ° pancreatic adenocarcinoma
• * Prostate cancer criteria:
• • castrate-resistant, metastatic prostate cancer;
• • high-risk prostate cancer (pending pathology definition)
• • Fluency in English, Haitian Creole, or Spanish as per self-report. Fluency is defined as an answer of "well" or "very well" on the screening questions for spoken ability
• • No prior cancer genetic counseling or germline testing for cancer risk as per self-report clinician's note, and/or no clinical documentation
• Exclusion Criteria:
• Phase 1:
• • Individuals of impaired decision-making capacity as per a clinician's or consenting professional's judgment.
• • Subjects who indicate level of fluency as "not at all" or "not well".
• Phase 2:
• • Individuals of impaired decision-making capacity as per a clinician's or consenting professional's judgment.
• • Subjects who indicate level of fluency as "not at all" or "not well".