Renal Function After Stentgraft Treatment Of Abdominal Aortic Aneurysm

Launched by VASTRA GOTALAND REGION · Feb 11, 2021

Keywords

ClinConnect Summary

This clinical trial is studying how different types of stentgrafts used to treat an abdominal aortic aneurysm (AAA) affect kidney function. An abdominal aortic aneurysm is a bulge in the large artery (aorta) that supplies blood to the abdomen, pelvis, and legs. The researchers want to see if using stentgrafts that are fixed above or below the aneurysm makes a difference in how well the kidneys work after the procedure.

To participate in this trial, individuals must be between the ages of 65 and 74 and have been diagnosed with a non-ruptured abdominal or iliac aneurysm. They should be able to give their written permission to participate and have the right type of blood vessel structure for the treatment. However, those who are currently on dialysis or have other specific health conditions may not be eligible. Participants will undergo a procedure to repair their aneurysm, and the study will track their kidney function afterward. This trial is currently looking for volunteers, and it’s an important step in understanding how these treatments can affect overall health, particularly kidney health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Willing and able to provide written informed consent
• • Meet criteria for non-ruptured infrarenal/iliac aneurysm
• • Suitable anatomy for treatment with an approved device (CE-marked) stentgraft according to the manufacturers' instructions for use for AAA.
• • Accepted for treatment with endovascular aortic repair (EVAR) by the participating vascular center.
• Exclusion Criteria:
• • Ongoing or planned dialysis
• • AAA treatment requiring stents or stentgrafts in renal and/or visceral arteries
• • Inability to independently complete HRQoL questionnaires due to language barriers
• • Anatomical preconditions that do not allow both types of fixation to be used interchangeably, i.e. very advanced suprarenal tortuosity (\>60 degrees), advanced suprarenal dilatation or infrarenal thrombus \>25% of circumference.