Reduction of Blood Recirculation in Veno-Venous ECMO
Launched by CHARITE UNIVERSITY, BERLIN, GERMANY · Feb 12, 2021
Trial Information
Current as of July 21, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a method to improve blood flow for patients who are on a special treatment called veno-venous ECMO (Extracorporeal Membrane Oxygenation) due to severe breathing problems, specifically a condition known as Acute Respiratory Distress Syndrome (ARDS). In this trial, researchers will measure something called the recirculation fraction (Rf), which is the part of the blood that doesn’t help improve oxygen levels in the body. By using this information, doctors hope to adjust the blood flow in the ECMO machine to make it more effective, while ensuring that patients still get enough oxygen.
To be eligible for the trial, participants need to be at least 18 years old and require veno-venous ECMO for their breathing issues caused by ARDS. Those who join the study can expect to have their blood flow carefully monitored and adjusted based on the measurements taken. The trial is currently recruiting participants, and it aims to find better ways to support patients who are critically ill and need extra help with breathing.
Gender
ALL
Eligibility criteria
- • Patients aged 18 years or older requiring veno-venous ECMO for treatment of refractory hypoxemia in ARDS.
About Charite University, Berlin, Germany
Charité - Universitätsmedizin Berlin is a leading academic medical center in Germany, renowned for its commitment to excellence in research, education, and patient care. As one of Europe's largest university hospitals, Charité integrates cutting-edge clinical practices with innovative research initiatives, fostering interdisciplinary collaboration across various medical fields. The institution is dedicated to advancing healthcare through rigorous clinical trials, contributing to the development of new therapies and treatment protocols. With a strong emphasis on translational medicine, Charité aims to bridge the gap between scientific discovery and practical application, ultimately enhancing patient outcomes and public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Berlin, , Germany
Patients applied
Trial Officials
Martin Russ, Dr. med.
Principal Investigator
Charite University Hospital Berlin
Philipp A Pickerodt, Dr. med.
Principal Investigator
Charite University Hospital Berlin
Vladimir Skrypnikov, Dr. med.
Principal Investigator
Charite University Hospital Berlin
Steffen Weber-Carstens, Prof. Dr. med.
Principal Investigator
Charite University Hospital Berlin
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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