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Search / Trial NCT04754854

Reduction of Blood Recirculation in Veno-Venous ECMO

Launched by CHARITE UNIVERSITY, BERLIN, GERMANY · Feb 12, 2021

Trial Information

Current as of July 21, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying a method to improve blood flow for patients who are on a special treatment called veno-venous ECMO (Extracorporeal Membrane Oxygenation) due to severe breathing problems, specifically a condition known as Acute Respiratory Distress Syndrome (ARDS). In this trial, researchers will measure something called the recirculation fraction (Rf), which is the part of the blood that doesn’t help improve oxygen levels in the body. By using this information, doctors hope to adjust the blood flow in the ECMO machine to make it more effective, while ensuring that patients still get enough oxygen.

To be eligible for the trial, participants need to be at least 18 years old and require veno-venous ECMO for their breathing issues caused by ARDS. Those who join the study can expect to have their blood flow carefully monitored and adjusted based on the measurements taken. The trial is currently recruiting participants, and it aims to find better ways to support patients who are critically ill and need extra help with breathing.

Gender

ALL

Eligibility criteria

  • Patients aged 18 years or older requiring veno-venous ECMO for treatment of refractory hypoxemia in ARDS.

About Charite University, Berlin, Germany

Charité - Universitätsmedizin Berlin is a leading academic medical center in Germany, renowned for its commitment to excellence in research, education, and patient care. As one of Europe's largest university hospitals, Charité integrates cutting-edge clinical practices with innovative research initiatives, fostering interdisciplinary collaboration across various medical fields. The institution is dedicated to advancing healthcare through rigorous clinical trials, contributing to the development of new therapies and treatment protocols. With a strong emphasis on translational medicine, Charité aims to bridge the gap between scientific discovery and practical application, ultimately enhancing patient outcomes and public health.

Locations

Berlin, , Germany

Patients applied

0 patients applied

Trial Officials

Martin Russ, Dr. med.

Principal Investigator

Charite University Hospital Berlin

Philipp A Pickerodt, Dr. med.

Principal Investigator

Charite University Hospital Berlin

Vladimir Skrypnikov, Dr. med.

Principal Investigator

Charite University Hospital Berlin

Steffen Weber-Carstens, Prof. Dr. med.

Principal Investigator

Charite University Hospital Berlin

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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