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Search / Trial NCT04755764

Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy

Launched by MARSHALL UNIVERSITY · Feb 12, 2021

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how three different medications—labetalol, atenolol, and nifedipine—affect blood flow and heart function in women during the early stages of pregnancy, specifically before 15 weeks. The goal is to understand how these medications can help manage high blood pressure that can occur in pregnancy, which is important for both the mother and baby’s health.

To participate in the trial, women aged 18 to 45 who speak English and are experiencing high blood pressure at the Maternal Hypertension Center at Cabell Huntington Hospital can join. Participants will take medication based on their individual health needs and will return for follow-up tests to measure how their body responds to the treatment. This research is vital as it could lead to better management of pregnancy-related high blood pressure, ensuring healthier outcomes for mothers and their babies.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Patients presenting to Maternal Hypertension Center at Cabell Huntington Hospital
  • English speaking
  • 18-45 years old.
  • Willing to provide informed consent
  • Gestational age prior to 15 weeks gestation
  • Exclusion Criteria:
  • Non-English speaking patients, patients
  • \<18 years old or \>45 years old
  • Not willing or able to provide consent
  • Gestational age \>15 weeks

About Marshall University

Marshall University, a distinguished institution located in Huntington, West Virginia, is dedicated to advancing healthcare through innovative research and clinical trials. With a robust focus on medicine, health sciences, and community engagement, the university collaborates with various stakeholders to conduct research that addresses critical health challenges. Marshall University leverages its state-of-the-art facilities and a team of experienced researchers to facilitate rigorous clinical trials, aiming to improve patient outcomes and contribute to the scientific community. Through its commitment to ethical practices and regulatory compliance, Marshall University strives to enhance the quality of life for individuals while fostering educational opportunities for future healthcare professionals.

Locations

Huntington, West Virginia, United States

Patients applied

0 patients applied

Trial Officials

Jesse Cottrell, MD

Principal Investigator

Marshall University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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