Active and Passive Exercise Training in Improving Vascular Function: Local vs Systemic Vascular Effect.
Launched by UNIVERSITY OF MILAN · Feb 12, 2021
Trial Information
Current as of July 23, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how different types of exercise can improve the health of blood vessels, which is important for keeping your heart and circulatory system in good shape. The study will compare two types of training: active exercise, like single leg knee extensions, and passive exercise, such as stretching without moving the muscles on your own. Over 8 weeks, researchers want to understand how these exercises affect blood flow in the arteries that supply the legs and other muscles in the body.
To participate in this trial, you should be between the ages of 18 and 65 and in generally good health, without serious nerve, blood vessel, or joint problems. If you're currently taking medications that affect your nerves or blood vessels, or if you've smoked recently, you may not be eligible. Participants can expect to take part in regular exercise sessions and will be monitored to see how their vascular function improves over the study period. This research could help us understand better ways to enhance blood flow and overall cardiovascular health.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • -
- Exclusion Criteria:
- • neurological, vascular and musculoskeletal disorders of the lower and upper limbs;
- • being on pharmacological therapy related to either neural and/or vascular response, including hormonal contraceptives and oral supplements;
- • being a current or former smoker;
- • having an irregular menstrual cycle (26 to 35 days) up to 3 months before the beginning of the study;
- • contraindications to joint mobilization; regular involvement in a SLKE or PS training programme.
About University Of Milan
The University of Milan is a prestigious academic institution renowned for its commitment to advancing medical research and education. With a strong emphasis on interdisciplinary collaboration, the university actively sponsors clinical trials aimed at enhancing healthcare outcomes and fostering innovation in medical science. Its research initiatives are guided by a dedication to ethical standards and rigorous scientific methodologies, ensuring that trials not only contribute to the body of knowledge but also prioritize patient safety and well-being. Through its extensive network of researchers and clinicians, the University of Milan plays a pivotal role in translating scientific discoveries into practical applications that benefit communities both locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Milano, , Italy
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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