Functioning of Elder Muscle; Understanding Recovery

Launched by UNIVERSITY OF NOTTINGHAM · Feb 19, 2021

Keywords

ClinConnect Summary

This clinical trial, titled "Functioning of Elder Muscle; Understanding Recovery," is studying how the muscles of older adults with frailty work, especially after they have suffered a hip fracture. As people age, they often lose muscle mass, which can lead to a higher risk of falls and slower recovery from injuries or surgeries. The researchers want to understand not just how much muscle someone has, but also how well that muscle functions and what it contains, like fats and proteins. They will also explore if the muscle’s health affects how well a person recovers after a hip fracture.

To be eligible for this study, participants need to be older adults who have a Clinical Frailty Score of 4 or higher, have sustained a hip fracture from a fall that requires surgery, and can understand and communicate in English. Participants can expect to undergo assessments that help researchers measure their muscle function and overall health. It’s important to know that certain individuals, such as those with specific medical conditions or who have fallen more than 12 hours before being hospitalized, will not be included in this study. This trial aims to improve our understanding of muscle health in older adults and how it affects recovery from injuries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Clinical Frailty Score (assessed as part of standard care) ≥ 4
• • Fractured hip, sustained following a fall, that requires surgery
• • Good understanding of spoken and written English language
• • Able to give informed consent, or availability of a legally acceptable surrogate to provide consent
• Exclusion Criteria:
• • Those who fell and sustained their hip fracture greater than 12 hours prior to hospitalisation.
• • Those who have fallen and sustained a hip fracture whilst an in-patient in hospital
• • Those who sustained the hip fracture as a result of high impact trauma (e.g. road traffic accident)
• • Surgery carried out later than 96 hrs after fall
• • Chronic neurological, inflammatory or musculoskeletal disorders which result in muscle wasting, e.g. Multiple sclerosis, muscular dystrophy, rheumatoid arthritis
• • Any co-morbidity which precludes hip surgery
• • Those with a compromised swallowing reflex which would prevent the participant from taking fluids orally, will be excluded.
• • Those taking diabetes medication