WashIn /WashOut Procedure To Prevent Agitation During Recovery After Inhalational Anesthesia With Sevoflurane

Launched by I.M. SECHENOV FIRST MOSCOW STATE MEDICAL UNIVERSITY · Feb 19, 2021

Keywords

ClinConnect Summary

This clinical trial is studying a new method called the Wash In/Wash Out procedure to help prevent agitation in patients recovering from inhalational anesthesia, specifically with a gas called sevoflurane. Agitation can happen after surgery and may lead to longer recovery times and other complications, so finding ways to reduce it is important. The goal of this trial is to see if this new technique can lower the chances of experiencing agitation during recovery from surgery.

To be eligible for this trial, participants need to be at least 18 years old, scheduled for open abdominal surgery under general anesthesia, and able to provide written consent. Unfortunately, patients who are pregnant, have certain mental health conditions, or are taking specific medications will not be able to participate. Those who join the study can expect to be monitored closely during their recovery, and their experiences will help researchers understand if this new procedure can improve recovery outcomes for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Written informed consent from participants
• • 2. Age ≥ 18 years
• • 3. Planned open abdominal surgery
• • 4. General anesthesia
• Exclusion Criteria:
• • 1. Pregnant patients and breastfeeding patients
• • 2. Mental disorders
• • 3. Epilepsy, Parkinson disease, Alzheimer, peripheral nerve and neuromuscular junction pathology (amyotrophic lateral sclerosis, Guillain-Barre Syndrome, myasthenia gravis et cet.)
• • 4. Use of antidepressants, antipsychotics, sedatives, psychoactive drugs within a month before surgery.