Behavioral Comparison of Three Different Graft Materials to Increase Soft Tissue Thickness Around Dental Implants.

Launched by UNIVERSITAT INTERNACIONAL DE CATALUNYA · Feb 20, 2021

Keywords

ClinConnect Summary

This clinical trial is studying how different types of graft materials can help improve the thickness of soft tissue around dental implants, which are artificial teeth roots placed in the jawbone. The researchers want to compare three types of materials: a graft taken from the patient's own palate, a porcine collagen matrix (a material made from pig skin), and a porcine acellular dermal matrix (another pig-derived material). They will look at how much soft tissue volume increases and how stable it is over time, specifically checking in at 3 and 15 months after the implant is placed.

To participate in this trial, patients should be at least 18 years old and need a single dental implant with some soft tissue issues, such as thin tissue or gaps. Key requirements include having enough bone structure for the implant and a healthy mouth with minimal plaque and bleeding. Participants can expect to undergo the usual procedure for a dental implant, along with receiving one of the graft materials. It's important to note that certain conditions, like pregnancy, active gum disease, or specific health issues, may prevent someone from joining the study. This research could help improve outcomes for dental implant patients by finding the best way to support the surrounding tissue.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients referred to Department of Periodontology (CUO) in need of a single implant and need of soft tissue augmentation such as buccal defects, thin biotype, lack of keratinized tissue and aesthetic compromised situation.
• • The patient must be ≥18 years and able to understand the nature of the proposed surgery and must sign an informed consent.
• • The implant must be located between 2 fixed reference points (i.e. clinical crowns).
• • Anterior and premolar teeth (from premolar to premolar).
• • Enough crestal bone width to leave a minimum thickness of 2mm at the buccal bone plate when placing the implant.
• • Palate must have ≥2mm of thickness at premolar area.
• • Full mouth plaque and bleeding score \<20%.
• Exclusion Criteria:
• • Pregnant or lactation.
• • Active periodontal disease.
• • Previous soft tissue augmentation in the area.
• • Need of guided bone regeneration (GBR) during or after the placement of the implant.
• • Heavy smokers (\> 10 cigarettes per day).
• • Local or systemic conditions that would interfere with routine periodontal therapy (non-controlled diabetes mellitus, cancer, HIV, Chronic High dose steroid therapy, bone metabolic diseases, radiation, immunosuppressive disorders, liver function disorder, immunosuppressant disease, autoimmune disease).
• • Allergy to non-steroidal anti-inflammatory drugs.
• • Patients taking medications that cause gingival enlargement.