Ketorolac in Palatoplasty

Launched by THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER, HOUSTON · Feb 24, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a medication called Ketorolac on patients undergoing a surgical procedure known as palatoplasty, which is often needed for children with cleft lip and palate. The researchers want to find out if adding Ketorolac to the usual pain management methods can help patients eat and drink better after their surgery. The trial is currently looking for participants who are 18 years or older and have a cleft palate, whether it’s complete or incomplete, and with or without a cleft lip.

To participate, patients must not have certain health issues, such as a history of serious heart problems or stomach ulcers, and cannot have had previous palate surgery. If eligible, participants will receive the usual care for pain, along with the Ketorolac, and their recovery, particularly how well they can eat and drink after surgery, will be monitored. This study aims to improve recovery experiences for those with cleft lip and palate, making it an important step in enhancing post-surgery care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • -Patient with Cleft palate (Complete and incomplete), with or without cleft lip, unilateral or bilateral
• Exclusion Criteria:
• • Syndromic Cleft Palate patients
• • Previous palatoplasty
• • Major unrepaired cardiac malformation
• • History of GI complications (GI Bleed, Gastric Ulceration)
• • History of Renal disorder
• • History of coagulopathy (As contraindication to NSAID use)
• • Feeding tube dependency
• • Patients whose parents refuse to consent to randomization