A Prospective, Randomized Controlled Study of the Probiotics as Adjuvant Treatment for Bacterial Vaginosis

Launched by PEKING UNIVERSITY SHENZHEN HOSPITAL · Feb 24, 2021

Keywords

ClinConnect Summary

This clinical trial is studying whether taking oral probiotics along with a vaginal medication called Metronidazole can help prevent bacterial vaginosis (BV) from coming back, compared to using Metronidazole alone. Bacterial vaginosis is a common condition that affects many women and can cause discomfort. The researchers want to see if adding probiotics can improve treatment outcomes.

To be part of this study, women between the ages of 18 and 55 who have been diagnosed with BV and are sexually active may be eligible. Participants will need to sign a consent form and should not have any serious health conditions, be pregnant, or have recently taken certain medications. If you join the trial, you can expect to take the probiotics for 30 days along with the Metronidazole for 7 days. The trial is currently looking for participants, and your involvement could help improve treatment options for BV in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Aged 18 to 55 years old, with history of sexual activity,
• • 2. Amsel criterion for diagnosing BV
• • 3. Sign informed consent
• Exclusion Criteria:
• • 1. History of systemic organic diseases or psychiatric diseases
• • 2. Planning for or during pregnancy, lactation, menstruation
• • 3. within 5 days of onset of the disease, any antibiotics has been used
• • 4. Long-term use of contraceptives or immunosuppressant
• • 5. Anaphylactic constitution or allergic to known ingredients of research drugs
• • 6. No same fixed partner (RSP) before and after treatment