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Search / Trial NCT04772768

Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease

Launched by AMSTERDAM UMC, LOCATION VUMC · Feb 22, 2021

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Coronary Artery Bypass Grafting Recurrent Angina Saphenous Vein Graft Dysfunction Advanced Coronary Artery Disease

ClinConnect Summary

This clinical trial is studying patients who have previously undergone coronary artery bypass grafting (CABG) and are experiencing chest pain or discomfort again, known as recurrent angina. The focus is on understanding how well their saphenous vein grafts (which are used in the surgery) are working and if their heart disease is getting worse. This research is important because it can help doctors determine the best ways to manage and treat patients with similar heart conditions in the future.

To participate in this study, patients should be between the ages of 65 and 90, have had CABG surgery, and be experiencing recurrent angina symptoms. Participants will be followed for several years, with information gathered from health records and phone assessments at 3 and 5 years after joining the study. This trial is currently recruiting, and it aims to gather a better understanding of heart health after bypass surgery, which could lead to improved care for patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Prior coronary artery bypass grafting
  • One or more saphenous vein grafts
  • Recurrent angina symptoms
  • Exclusion Criteria:
  • \<18 years of age
  • ≥ 90 years of age
  • Cardiogenic shock
  • Pregnancy
  • Failure to provide informed consent

About Amsterdam Umc, Location Vumc

Amsterdam UMC, located at VU Medical Center (VUmc), is a leading academic medical center in the Netherlands dedicated to advancing healthcare through innovative research and clinical trials. With a strong emphasis on translating scientific discoveries into practical applications, Amsterdam UMC collaborates closely with researchers, healthcare professionals, and industry partners to enhance patient outcomes. The institution is committed to rigorous ethical standards and regulatory compliance, ensuring the integrity and reliability of its clinical research initiatives across various medical disciplines.

Locations

Amsterdam, , Netherlands

Patients applied

0 patients applied

Trial Officials

Paul Knaapen, Professor

Principal Investigator

Amsterdam University Medical Centers, Department of Cardiology

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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