Neutrophil Phenotypic Profiling and Surgical Site Infections in Surgical Patients
Launched by BOSTON CHILDREN'S HOSPITAL · Feb 23, 2021
Trial Information
Current as of June 27, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is investigating how certain immune cells, called neutrophils, behave in patients who are having surgery. The main goal is to understand if the way these cells function can help predict the risk of surgical site infections (SSIs), which are infections that can occur after surgery and often lead to longer hospital stays and higher medical costs.
To participate in this study, individuals must be scheduled for specific types of surgery, such as open gastrointestinal surgery or spine fusion surgery. People who are taking drugs that weaken their immune system or have certain immune-related diseases cannot join. If eligible, participants can expect to have their neutrophil function assessed before and after their surgery, which may help improve future care for patients undergoing similar procedures. The trial is currently recruiting patients of all ages, ensuring a wide range of experiences and insights.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • scheduled for an elective open gastrointestinal surgical procedure or spine fusion surgery
- Exclusion Criteria:
- • On chronic immunosuppressive drugs such as chronic corticosteroid use
- • preexisting immunodeficiency diseases
About Boston Children's Hospital
Boston Children's Hospital is a leading pediatric healthcare institution renowned for its commitment to advancing child health through innovative research and exceptional clinical care. As a prominent clinical trial sponsor, the hospital leverages its extensive expertise in pediatric medicine to conduct rigorous and ethically sound research studies aimed at improving treatment options and outcomes for children. With a collaborative approach that integrates cutting-edge technology and multidisciplinary teams, Boston Children's Hospital is dedicated to translating scientific discoveries into practical applications that enhance the well-being of young patients and their families.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Boston, Massachusetts, United States
Patients applied
Trial Officials
Koichi Yuki, MD
Principal Investigator
Boston Children's Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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