Iohexol Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Feb 26, 2021

Keywords

ClinConnect Summary

This clinical trial is focused on understanding how well the kidneys filter blood in critically ill patients who have a condition called augmented renal clearance, which means their kidneys are working more efficiently than usual. To do this, researchers will use a special test involving a substance called iohexol, which helps measure the kidney's filtering ability. The goal is to gather important information that could improve care for patients with similar conditions in the future.

To be part of this study, participants must be adults aged 65 to 74 who are currently in the Intensive Care Unit (ICU) and have a certain level of kidney function. They also need to have a urinary catheter in place and be part of a social security program. However, pregnant individuals, those with allergies to contrast media, or anyone who had a CT scan with contrast on the day of joining the study will not be eligible. If someone chooses to participate, they will undergo the iohexol test, which is a safe procedure that helps doctors learn more about their kidney function during a critical time in their health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ICU patient
• • 24h Creatinine clearance \>130ml/min/1.73m2
• • Urinary catheterization
• • Affiliation to a social security scheme
• Exclusion Criteria:
• • Pregnancy
• • CT-scan with contrast media infusion the day of inclusion
• • Documented allergy to contrast media
• • Patient under guardianship / curatorship
• • Patient benefiting from the "State Medical Assistance"