Role of Toilet Bronchoscopy in RICU
Launched by ASSIUT UNIVERSITY · Mar 11, 2021
Trial Information
Current as of June 29, 2025
Unknown status
Keywords
ClinConnect Summary
Aim Of Work To study the value of toilet bronchoscopy in
1. Mechanical ventilated patients with chest disease and copious secretion.
2. Mechanical ventilated patients diagnosed to have atelectasis radiologically.
3. Patients on non-invasive ventilation with chest diseases and copious secretion
4. Compare Different types of mucolytics during toilet bronchoscopy in mechanically ventilated patients.
5. Compare Different types of sedations during toilet bronchoscopy in mechanically ventilated patients.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • • Patients on mechanical ventilation with underlying dieases that are characterized with mucus overproduction such as asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and cystic fibrosis.
- • Patients on mechanical ventilation with visible large amount of sputum during suction in order to clear secretions.
- • Patients on mechanical ventilation with radiologically diagnosed atelectasis and absent air-bronchograms
- • Patient on NIV who was benefit from toilet bronchoscopy to clear retained secretion.
- • Exclusion Criteria:Absolute contraindications
- • Absence of consent from the patient or his/her representative.
- • Inability to adequately oxygenate the patient during the procedure.
- • Current myocardial ischaemia.
- • Significant haemodynamic instability.
- • Life-threatening cardiac arrhythmias.
- • Current significant bronchospasm.
- • Undrained pneumothorax.
- • Relative contraindications
- • Thrombocytopenia (platelet count ≤50,000 platelets/mm).
- • INR of 2 or greater, or an elevated PTT.
- • BUN \>30.
- • severe tracheal obstruction.
- • Recent myocardial ischaemia and/or unstable angina.
- • Intracranial hypertension.
- • Poorly-controlled heart failure.
- • Recent oral intake.
About Assiut University
Assiut University, a prominent academic institution located in Egypt, is dedicated to advancing medical research and clinical trials that enhance healthcare outcomes. With a strong emphasis on innovation and collaboration, the university engages in a wide array of clinical studies across various disciplines, aiming to contribute valuable insights into disease prevention, diagnosis, and treatment. Assiut University's commitment to ethical research practices and rigorous scientific methodology ensures the integrity and reliability of its clinical trials, ultimately benefiting both the local community and the global medical landscape.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Assiut, , Egypt
Patients applied
Trial Officials
Saher f youssif
Principal Investigator
Assiut University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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