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Search / Trial NCT04798118

Role of Toilet Bronchoscopy in RICU

Launched by ASSIUT UNIVERSITY · Mar 11, 2021

Trial Information

Current as of June 29, 2025

Unknown status

Keywords

ClinConnect Summary

Aim Of Work To study the value of toilet bronchoscopy in

1. Mechanical ventilated patients with chest disease and copious secretion.
2. Mechanical ventilated patients diagnosed to have atelectasis radiologically.
3. Patients on non-invasive ventilation with chest diseases and copious secretion
4. Compare Different types of mucolytics during toilet bronchoscopy in mechanically ventilated patients.
5. Compare Different types of sedations during toilet bronchoscopy in mechanically ventilated patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Patients on mechanical ventilation with underlying dieases that are characterized with mucus overproduction such as asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and cystic fibrosis.
  • Patients on mechanical ventilation with visible large amount of sputum during suction in order to clear secretions.
  • Patients on mechanical ventilation with radiologically diagnosed atelectasis and absent air-bronchograms
  • Patient on NIV who was benefit from toilet bronchoscopy to clear retained secretion.
  • Exclusion Criteria:Absolute contraindications
  • Absence of consent from the patient or his/her representative.
  • Inability to adequately oxygenate the patient during the procedure.
  • Current myocardial ischaemia.
  • Significant haemodynamic instability.
  • Life-threatening cardiac arrhythmias.
  • Current significant bronchospasm.
  • Undrained pneumothorax.
  • Relative contraindications
  • Thrombocytopenia (platelet count ≤50,000 platelets/mm).
  • INR of 2 or greater, or an elevated PTT.
  • BUN \>30.
  • severe tracheal obstruction.
  • Recent myocardial ischaemia and/or unstable angina.
  • Intracranial hypertension.
  • Poorly-controlled heart failure.
  • Recent oral intake.

About Assiut University

Assiut University, a prominent academic institution located in Egypt, is dedicated to advancing medical research and clinical trials that enhance healthcare outcomes. With a strong emphasis on innovation and collaboration, the university engages in a wide array of clinical studies across various disciplines, aiming to contribute valuable insights into disease prevention, diagnosis, and treatment. Assiut University's commitment to ethical research practices and rigorous scientific methodology ensures the integrity and reliability of its clinical trials, ultimately benefiting both the local community and the global medical landscape.

Locations

Assiut, , Egypt

Patients applied

0 patients applied

Trial Officials

Saher f youssif

Principal Investigator

Assiut University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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