Human Milk Fortification With Adjustable Versus Targeted Method

Launched by UNIVERSITY OF CALGARY · Mar 18, 2021

Keywords

ClinConnect Summary

This clinical trial is investigating whether preterm infants who weigh less than 1250 grams (about 2.75 pounds) gain weight more effectively when given human milk that is fortified using a targeted method compared to an adjustable method. The researchers believe that the targeted approach, which tailors the fortification to meet the specific needs of each baby, may help these vulnerable infants grow better.

To be eligible for the study, infants must be born at Foothills Medical Centre, weigh less than 1250 grams, and be considered appropriate for their gestational age. Unfortunately, infants with certain health conditions or infections, or those who have had significant medical issues like major congenital anomalies, cannot participate. If your baby qualifies and joins the study, they will receive one of the two types of fortified milk, and the team will monitor their weight gain closely. This research is important as it could help improve the growth and health outcomes for premature infants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Infants with birth weight \<1250 g born at Foothills Medical Centre.
• • Appropriate for gestational age (AGA) (according to Fenton's Charts).
• Exclusion Criteria:
• • Abnormal Newborn Metabolic Screen
• • Major congenital anomalies intervention.
• • Patients who develop NEC prior to enrollment.
• • Patients with confirmed congenital Toxoplasmosis, Syphilis, Rubella, Cytomegalovirus, Herpes simplex virus, Varicella and/or Zika (TORCH infections).
• • Patients receiving systemic steroids.
• • Patients with acute kidney injury (AKI).