Study of the Involvement of Fatty Acids in Retinopathy of Prematurity: Relationship Between Retinopathy of Prematurity and the Rate of Expression of Transplacental Fatty Acid Receptors.

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DIJON · Mar 25, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the role of certain fatty acids in a condition called retinopathy of prematurity (ROP), which affects the eyes of premature babies. ROP can happen when the blood vessels in the retina (the part of the eye that helps us see) do not develop properly, and this study aims to understand how the levels of omega-3 fatty acids in mothers and their premature babies may influence this condition. Researchers want to learn more about how these fatty acids are absorbed and processed by the mother and the baby to see if this could help prevent ROP.

To participate in this study, mothers must be 18 years or older and either have given birth to a premature baby (less than 29 weeks of pregnancy) or a full-term baby (between 39 weeks and 41 weeks plus 6 days). Mothers who are critically ill or have certain health conditions affecting their pregnancy are not eligible. Participants will be asked to provide information and possibly undergo tests related to the fatty acids, helping researchers improve understanding and treatment of ROP in premature infants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Mothers giving birth to premature babies less than 29 weeks of amenorrhea (WA), after obtaining their non-opposition.
• • 2. Mothers giving birth at term between 39 and 41WA+6 days, after obtaining their non-opposition.
• • 3. ≥18 years
• • 4. Mothers not under legal protection
• Exclusion Criteria:
• • 1. Mothers giving birth between 29WA and 38WA+6 days
• • 2. Mothers in critical condition.
• • 3. Person not affiliated to national health insurance
• • 4. For full-term mothers: patient presenting or having presented a health condition that affected a previous pregnancy (vascular such as pregnant hypertension, preeclampsia; gestational diabetes; intrauterine growth retardation, maternal infection during pregnancy such as toxoplasmosis, cytomegalovirus, rubella, measles, chickenpox).