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Search / Trial NCT04827290

Assessment of the Effect of Restriction on Alimentary AGE in Progression of Chronic Kidney Disease

Launched by CENTRE HOSPITALIER SAINT JOSEPH SAINT LUC DE LYON · Mar 30, 2021

Trial Information

Current as of August 25, 2025

Not yet recruiting

Keywords

Kidney Failure Advanced Glycation Products Chronic Kidney Disease

ClinConnect Summary

This clinical trial is studying how different diets can affect people with moderate chronic kidney disease (CKD), specifically those in stages IIIA and IIIB. The researchers want to compare two types of diets: one that includes normal protein but is low in advanced glycation end products (AGEs), which are harmful compounds found in certain cooked foods, and another that has normal protein but is high in AGEs. The goal is to see if changing the way people eat can help slow down the progression of kidney disease.

To participate in this study, you need to be between 18 and 89 years old and have been diagnosed with stage IIIA or IIIB chronic kidney disease. You also need to be able to give your consent to join the trial. Unfortunately, if you have acute kidney failure or are already following a low-AGE diet, you won't be eligible to participate. If you join the study, you can expect to follow one of the two diets and help the researchers learn more about how diet impacts kidney health. The trial is not yet recruiting participants, but it aims to gather important information that could benefit others with kidney disease in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with a grade IIIA-B CKD (GFR with CKD-EPI ≥ 30 mL/min and \< 60mL/min)
  • Informed consent signed
  • Aged 18 to 89 years
  • Exclusion Criteria:
  • Protected adult
  • Acute renal failure
  • Patient already on a low-AGE diet (\< 1kU AGE/day) following a dietetic consultation
  • Current participation in another interventional research

About Centre Hospitalier Saint Joseph Saint Luc De Lyon

Centre Hospitalier Saint Joseph Saint Luc de Lyon is a prominent healthcare institution dedicated to providing high-quality medical care and advancing clinical research. Located in Lyon, France, the hospital is renowned for its comprehensive range of services and a commitment to patient-centered care. As a clinical trial sponsor, the Centre Hospitalier Saint Joseph Saint Luc actively engages in innovative research initiatives aimed at improving treatment outcomes and enhancing healthcare practices. The institution collaborates with multidisciplinary teams and leverages cutting-edge methodologies to contribute to the advancement of medical knowledge and the development of new therapeutic approaches.

Locations

Lyon, , France

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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