Myocardial Ischemia Without Obstructive Coronary Stenoses

Launched by HOSPITAL SAN CARLOS, MADRID · Mar 30, 2021

Keywords

ClinConnect Summary

This clinical trial is studying a condition called myocardial ischemia, which is when the heart doesn't get enough blood flow, but the cause is not due to a blockage in the main heart arteries. Instead, it explores issues like problems with small blood vessels or unusual reactions in blood flow. The goal is to gain a better understanding of these non-blocking heart problems, which can affect many people.

To participate in this trial, you need to be at least 18 years old and give written consent. You should be eligible for specific heart tests that involve medications like adenosine or acetylcholine. However, this trial is not for everyone—people who have certain heart issues, serious health problems, or who cannot take these medications will not be able to join. If you participate, you can expect to undergo some tests to help researchers learn more about your heart's condition. Overall, this trial aims to shed light on heart issues that don’t involve traditional blockages, helping to improve understanding and treatment options for those affected.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Written informed consent available.
• • Age ≥ 18 years.
• • Patient eligible for invasive physiological assessment with adenosine and / or acetylcholine.
• Exclusion Criteria:
• • Hemodynamic instability.
• • Anticipated technical issues for physiology wire measurements.
• • Culprit vessel of acute coronary syndrome
• • Contraindications for adenosine administration.
• • Contraindications for acetylcholine test.
• • Reduced life expectancy (less than 1 year).