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Search / Trial NCT04828954

Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb

Launched by UNIVERSITY OF CHICAGO · Mar 30, 2021

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Thumb Carpometacarpal Joint Osteoarthritis Rehabilitation Hand Therapy

ClinConnect Summary

This clinical trial is studying the best way to keep the thumb still after surgery for thumb osteoarthritis, a condition that can cause pain and stiffness, especially in middle-aged and older women. The researchers want to find out if keeping the thumb in a cast or splint for different lengths of time after surgery helps people recover better and faster. Participants in the trial will either wear a splint for 2 weeks or a splint that changes to a cast for a total of 6 weeks. By comparing these two groups, the study aims to help doctors create a more effective recovery plan for patients after thumb surgery.

To join the study, participants need to be at least 40 years old and planning to have specific thumb surgeries, such as trapeziectomy. However, those who have had previous thumb surgeries or have certain other medical conditions won’t be eligible. Throughout the study, participants will provide feedback about their recovery and be monitored to see how well they are doing. This information could lead to better treatment options for future patients with similar thumb issues.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age \>= 40 years old
  • * Patients undergoing arthroplasty of the first CMC joint including:
  • 1. Trapeziectomy with LRTI
  • 2. Simple Trapeziectomy
  • 3. Suspensionplasty (suture vs. APL)
  • Exclusion Criteria:
  • Patients \< 40 years of age
  • Patients who have undergone prior surgical procedures on the thumb base
  • Patients with history of prior procedure at the base of thumb, or those with plan for concomitant carpal tunnel release or thumb metacarpophalangeal (MCP) arthrodesis, will be excluded. Concomitant carpal tunnel surgery may skew outcome surveys, and an arthrodesis procedure will warrant a longer length of immobilization following procedure.
  • Those undergoing implant arthroplasty
  • Patients with a diagnosis of inflammatory arthritis
  • Patients with diagnosis of hypermobility syndrome

About University Of Chicago

The University of Chicago is a prestigious research institution renowned for its commitment to advancing medical science through innovative clinical trials. With a robust infrastructure that supports multidisciplinary collaboration, the University actively engages in cutting-edge research across various therapeutic areas. Its dedicated team of experienced investigators and state-of-the-art facilities enable the University of Chicago to conduct rigorous clinical studies aimed at improving patient outcomes and translating scientific discoveries into tangible healthcare solutions. The institution prioritizes ethical standards and patient safety, ensuring that all trials adhere to the highest regulatory guidelines and best practices in clinical research.

Locations

Chicago, Illinois, United States

Patients applied

BR

1 patients applied

Trial Officials

Jennifer Wolf, MD

Principal Investigator

University of Chicago

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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