Eccentric Manual Resistance Training in Patients With Ischemic CMP
Launched by VIENNA HOSPITAL ASSOCIATION · Mar 31, 2021
Trial Information
Current as of July 08, 2025
Completed
Keywords
ClinConnect Summary
BACKGROUND: Eccentric resistance training demonstrated positive effects in ischemic cardiomyopathy patients in several studies. These studies were mainly set on device-based training interventions comparing eccentric-orientated and concentric-orientated training. Eccentric-orientated training induced comparable positive effects on cardiac and functional levels and even better effects on muscle strength improvement.
RESEARCH AIMS: The aim of the study is to determine if eccentric-orientated body weight and manual resistance training in ischemic cardiomyopathy patients will allow a more sign...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Male / female, 45-85a
- • Ischemic cardiomyopathy with mildly reduced ejection fraction (40 -50%)
- • Coronary heart disease
- Exclusion Criteria:
- • Acute coronary syndrome, myocarditis or pericarditis in the last 3 months
- • Cardiac decompensation in the last 3 months
- • Severe symptomatic heart failure NYHA IV (New York Heart Association)
- • Device - carrier (ICD= Intracardial Defibrillator, CRT= Cardiac Resynchronization Therapy, PM=Pacemaker)
- • Hemodynamically significant valvular disease
- • Symptomatic cardiac arrhythmia
- • Intractable, uncontrolled hypertension (repetitive blood pressure \> 150/100)
- • Severe comorbidities, which lead to study exclusion by the investigator
- • Pregnancy / nursing
About Vienna Hospital Association
The Vienna Hospital Association (Wiener Gesundheitsverbund) is a leading healthcare institution in Austria, dedicated to providing high-quality medical services and advancing clinical research. With a network of hospitals and specialized clinics, it aims to enhance patient care through innovative therapies and comprehensive clinical trials. The association prioritizes collaboration between healthcare professionals and researchers to foster advancements in medical science, ensuring that cutting-edge treatments are accessible to diverse patient populations. Committed to excellence in research and patient outcomes, the Vienna Hospital Association plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Vienna, , Austria
Patients applied
Trial Officials
Walter Bily, MD
Principal Investigator
Vienna HA
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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