Microbiome and Polycystic Ovaries

Launched by SHEBA MEDICAL CENTER · Apr 6, 2021

Keywords

ClinConnect Summary

This clinical trial, titled "Microbiome and Polycystic Ovaries," is looking into how the bacteria in the gut and vaginal area might affect women with Polycystic Ovary Syndrome (PCOS). PCOS is a common health issue that can cause problems with hormone levels, fertility, and mental health. The researchers want to see how different treatments might change the types of bacteria in these areas and how those changes relate to the different symptoms of PCOS.

To participate in this study, women aged 18 to 45 who have been diagnosed with PCOS and are starting a new treatment may be eligible. There is also a control group for women without PCOS. However, women with certain other health conditions, those who have recently taken specific medications, or those with infections will not be included. Participants can expect to provide samples for testing and contribute to important research that could help improve understanding and treatment of PCOS.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Study group: Untreated women diagnosed with PCOS that are planned for intervention.
• • Control group: Women without PCOS visiting the gynecologic outpatient's clinics.
• Exclusion Criteria:
• • 1. Endocrine abnormality ( Cushing's syndrome, congenital adrenal hyperplasia, thyroid disorder, hyperprolactinemia and androgen-secreting tumor).
• • 2. Premature ovarian failure 2. Active malignancy 3. Participants taking antibiotics/ probiotics, hormonal, vaginal or laxative medicine (in the previous week).
• • 4. Vaginitis/ Pelvic Inflammatory Disease (PID)