Dengue Vaccine Strategy in Children Aged 9 to 17 Years in the French Caribbean

Launched by UNIVERSITY HOSPITAL CENTER OF MARTINIQUE · Apr 7, 2021

Keywords

ClinConnect Summary

The DengueSEA study is focused on understanding how common dengue virus infections are among children aged 9 to 17 years in the French Caribbean islands of Martinique and Guadeloupe. Dengue fever is a serious illness spread by mosquitoes, and while there is no specific treatment, a vaccine called Dengvaxia® has been approved to help prevent it in people who have already been infected with the virus. This study aims to find out how many children in this age group have been exposed to the dengue virus by analyzing blood samples taken during their hospital visits.

To participate, children must be between 9 to 17 years old, have been living in Martinique or Guadeloupe for at least a year, and need a blood sample taken for medical reasons. It's important that they do not have a fever or any signs of infection at the time of the study. Parents or legal guardians will also have the chance to take part in a survey about the acceptability of the vaccine. By joining this study, families can help provide valuable information that could improve dengue vaccination strategies for children in their region.

Gender

ALL

Eligibility criteria

• • CHILDREN
• Inclusion Criteria for children:
• • Any child aged 9 to 17 years presenting to one of the hospital departments participating in the study at the University Hospitals of Martinique or Guadeloupe
• • Need to take a blood sample or place a peripheral venous line for the management of the child
• • Residence in Martinique or Guadeloupe since at least one year
• • Information on the study given to the child and his/her parent or legal guardian
• • Collection of the parent's or legal guardian's non-objection to the child's participation
• Exclusion Criteria for children:
• • Presence of fever or suspected acute infection
• • Presence of an immune deficiency or any other dysimmune condition
• • PARENTS
• • Parental inclusion criteria ("vaccine acceptability" survey)
• • Collection of the parent's or legal guardian's non-objection to participate in the Dengvaxia® vaccine acceptability survey
• • Comprehension of spoken and written French
• • Non-inclusion criteria for parents (vaccine acceptability survey)
• • - None of the above