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Search / Trial NCT04843644

Microbiota and Symptom Distress in Head and Neck Cancer Patients Receiving Radiotherapy

Launched by TAIPEI MEDICAL UNIVERSITY · Apr 12, 2021

Trial Information

Current as of June 27, 2025

Not yet recruiting

Keywords

Head And Neck Cancer Mucositis Honey Taiwanese Green Propolis Intelligent Care Microbiota Symptoms Distress

ClinConnect Summary

This clinical trial is exploring how different treatments can help patients with head and neck cancer who are experiencing a painful condition called oral mucositis, which is often caused by radiation therapy. The study will look at how common and severe mucositis is, and it will compare the effectiveness of honey, a natural substance called Taiwan green propolis, and standard care in managing this condition. Researchers will also monitor changes in symptoms using a smart bracelet and analyze saliva and stool samples to understand the role of bacteria in the mouth and gut.

To participate in this trial, you need to be at least 20 years old, have been diagnosed with head and neck cancer, and be planning to receive radiation therapy. It’s important that you can understand and communicate in Mandarin or Taiwanese, as you’ll need to fill out some questionnaires. If you have allergies to honey or propolis, mental health issues, diabetes, or are nearing the end of life, you won’t be eligible for this study. Participants will help researchers gather valuable information that could lead to better treatments for mucositis in cancer patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • - age≧20 years old diagnosed as head and neck cancer patients Plan to Receive radiation therapy Consciousness, ability to complete research assessment and willing to participate in research Patients can be communicated in Mandarin and Taiwanese, and complete the questionnaire on their own or with the help of researchers.
  • Exclusion Criteria:
  • - History of allergic to honey, propolis, various pollen, alcohol People with mental disorders or cognitive dysfunction Diabetes mellitus Critical of end of life patient

About Taipei Medical University

Taipei Medical University (TMU) is a leading educational and research institution located in Taipei, Taiwan, dedicated to advancing health sciences and clinical research. Established with a focus on fostering innovation in medical education, TMU integrates comprehensive clinical training with rigorous research methodologies. The university is committed to improving patient outcomes through a strong emphasis on translational medicine and interdisciplinary collaboration. TMU's clinical trial initiatives are designed to explore new treatments and therapies, contributing to the global body of medical knowledge while adhering to the highest ethical standards and regulatory compliance.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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