Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease

Launched by RWTH AACHEN UNIVERSITY · Apr 15, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the activity of the sympathetic nervous system (SNA) in patients with Chronic Obstructive Pulmonary Disease (COPD). The sympathetic nervous system is responsible for the body's "fight or flight" response, which can affect heart rate and blood flow. Researchers want to understand how SNA is increased in COPD patients and what causes this change. They will explore whether conditions like sleep apnea and pulmonary hypertension (high blood pressure in the lungs) are linked to higher SNA levels in these patients.

To participate in the trial, you need to be at least 18 years old and able to give your consent to take part. However, if you have certain heart conditions like atrial fibrillation or are currently hospitalized, you may not be eligible. Participants can expect a thorough examination using advanced technology to measure nerve activity and gain insights into their condition. This study aims to fill a gap in understanding how COPD affects the nervous system, which could lead to better treatment options in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18
• • Ability and willingness to give informed consent to participate in the study
• Exclusion Criteria:
• • Atrial fibrillation
• • Active pacing of the heart by a cardiac pacemaker (i.e. no intrinsic heart rate)
• • Clinically pre-established cardiovascular disease (e.g. arterial hypertension or systolic heart failure)
• • In-patient stay in the hospital within the last 4 weeks prior to the study examination date