the SDMEAI Study: a Multi-center Epidemiological Study
Launched by SUN YAT-SEN UNIVERSITY · Apr 15, 2021
Trial Information
Current as of June 28, 2025
Not yet recruiting
Keywords
ClinConnect Summary
The SDMEAI Study is a research project that aims to understand how certain diseases and medications affect the eyes. Many patients with conditions related to rheumatology, immunology, nephrology, and gastroenterology may experience eye problems, which can seriously impact their daily lives. This study will look at patients with these systemic diseases to gather information on how often these eye issues occur and what factors might contribute to them. Researchers also plan to create an artificial intelligence model to help predict eye problems based on collected data.
To participate in this study, individuals aged 6 to 80 who have been diagnosed with systemic diseases and have either used or not used certain medications that may affect the eyes are welcome. Participants should not have a history of specific eye conditions or surgeries that could interfere with the study. Those who join can expect to be followed for at least two years, providing valuable information that can help improve the understanding and management of eye-related issues in patients with systemic diseases.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age 6-80 years old, gender is not limited
- • patients who have been diagnosed with systemic diseases;
- • patients who have ever or never used any ocular toxic drugs such as corticosteroids, chloroquine, etc.;
- • no history of glaucoma, cataract, scleritis, uveitis, ocular trauma, etc. before enrollment;
- • willing to complete follow-ups for at least 2 years.
- Exclusion Criteria:
- • Mainly use local therapies (intraocular, intra-articular and other non-systemic drug routes);
- • history of intraocular surgery (such as lens implantation, vitrectomy, retinal photocoagulation);
- • history of glaucoma, cataract, center serous retinopathy, etc.;
- • history of various diseases (such as scleritis, uveitis, eye trauma, etc.) that may cause opacity of the eye under the posterior capsule;
- • any other diseases or conditions that affect the observation, such as diabetes, low calcium convulsions, long-term exposure to radiation before enrollment;
- • subjects with endogenous corticosteroids, or psychiatric diseases.
About Sun Yat Sen University
Sun Yat-sen University, a prestigious institution located in Guangzhou, China, is dedicated to advancing medical research and healthcare innovations. As a leading clinical trial sponsor, the university leverages its extensive academic resources and collaboration with top-tier medical professionals to conduct rigorous clinical studies. Committed to improving patient outcomes and contributing to global health knowledge, Sun Yat-sen University focuses on a wide range of therapeutic areas, employing cutting-edge methodologies to ensure the integrity and efficacy of its research initiatives. Through its clinical trials, the university aims to foster scientific advancements and enhance the quality of care provided to patients both locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Haotian Lin, Ph.D.
Principal Investigator
Zhongshan Ophthalmic Center, Sun Yat-sen University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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