Impact Study of Cholera Vaccination in Endemic Areas - Clinical Surveillance

Launched by EPICENTRE · Apr 16, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a cholera vaccine in areas where cholera is common, specifically in both urban and rural parts of the Democratic Republic of Congo (DRC). The goal is to understand how well mass vaccination campaigns can help control cholera outbreaks and reduce the number of deaths caused by this disease. By gathering this information, researchers hope to create better strategies for using the cholera vaccine in places that face high rates of infection.

If you or a family member are seeking treatment for cholera at one of the selected treatment centers, you may be eligible to participate in the study. To join, you need to meet certain criteria, like being diagnosed with cholera and providing consent to participate. If you're under 18, you will need permission from a parent or guardian. Participants will help researchers gather important information about cholera and its spread. It's important to know that if you choose not to participate, that decision will be respected, and it won't affect your care.

Gender

ALL

Eligibility criteria

• • For Surveillance in study CTCs
• Inclusion Criteria:
• • All patients presenting at the time of the study to any selected Cholera Treatment Center/Cholera Treatment Unit (CTC/CTU), matching the case definition and giving his/her consent (or assent for children 8 to 17 years old) to participate in the study will be eligible.
• Exclusion Criteria:
• • Patients who decline to participate will be excluded from the study.
• Follow up of individuals with active cholera shedding:
• Inclusion Criteria:
• • 1. present to any selected CTC/CTU, match the case definition, participate to the clinical surveillance activity and test positive to RDT OR
• • 2. Be a household member of a person respecting inclusion criteria 1. AND for whom the head of the household has provided verbal consent to participate AND giving his/her consent (or assent for children 8 to 17 years old) to participate in the study will be eligible.
• Exclusion Criteria:
• • - Individuals who decline to participate will be excluded from the study, as well as households for whom the head of the household (and his or her representative) decline the participation of his/her household.