Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones

Launched by AL-AZHAR UNIVERSITY · Apr 21, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the best ways to treat medium-sized kidney stones that are not located in the lower part of the kidney. Researchers want to compare three different treatment methods: mini-percutaneous nephrolithotomy (mini-PNL), retrograde intrarenal surgery (RIRS), and extracorporeal shockwave lithotripsy (SWL). The goal is to find out which method removes the stones most effectively, is the safest, costs the least, and provides the most satisfaction for both patients and doctors.

To participate in this study, you need to be an adult with a single kidney stone that measures between 10 and 20 millimeters and is dense (hard to break apart). However, there are some exclusions; for instance, if you are pregnant, have certain health conditions, or have a severe urinary tract infection, you won’t be eligible. If you join the trial, you will be placed into one of the three treatment groups and will have regular follow-ups for three months after the procedure to monitor your recovery and the effectiveness of the treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patients (both genders)
• • Single non-lower pole renal stone.
• • Stone size: 10-20 mm.
• • Stone density: \> 1000 HU.
• Exclusion Criteria:
• • Pregnant women.
• • Morbid obesity.
• • Severe orthopaedic deformities.
• • Co-morbidities precluding general anaesthesia or prone positioning.
• • Uncorrectable coagulation disorders.
• • Active urinary tract infection (UTI).
• • Stone in a calyceal diverticulum.
• • Abnormal renal anatomy.
• • Urinary tract obstruction distal to the stone.
• • Concomitant pathology that needs intervention in the same setting.
• • Advanced hydronephrosis.