Quality of Life Assessment Between Internal Endoscopic Versus Percutaneous Drainage in Biliary Obstruction

Launched by MAYO CLINIC · Apr 21, 2021

Keywords

ClinConnect Summary

This clinical trial is studying how different treatments for biliary obstruction affect patients' quality of life. Biliary obstruction occurs when the bile ducts, which help with digestion, become blocked. The trial is comparing two methods: endoscopic retrograde cholangiopancreatography (ERCP), which is a procedure where doctors use a camera and tools to clear the blockage, and percutaneous trans-hepatic biliary drainage (PTBD), which involves placing a tube through the skin to help drain bile. The goal is to see which method helps patients feel better and improves their daily lives, whether they have benign (non-cancerous) or malignant (cancerous) conditions.

To participate in the study, patients should be between the ages of 65 and 74 and have either benign or malignant biliary obstruction. They must also be planning to undergo either the ERCP or PTBD procedure. Unfortunately, patients with gallstone disease, those who have already had one of these procedures before, and certain vulnerable populations, like pregnant women or prisoners, cannot participate. If you join the trial, you can expect to be monitored for how these treatments affect your overall well-being, and your experiences will help improve care for future patients with similar conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with benign biliary obstruction
• • Patients with malignant biliary obstruction
• • Patients undergoing ERCP and/or PTBD
• Exclusion Criteria:
• • Patients with gallstone disease
• • Patients who will undergo ERCP who have previously underwent a PTBD
• • Patients who will undergo PTBD who have previously underwent an ERCP
• • Female patients who are pregnant
• • Prisoners and other vulnerable populations