Evolution of Balance and Vestibular Function in Patients Treated With Gammaknife Radiosurgery for Vestibular Schwannoma

Launched by UNIVERSITY HOSPITAL, TOULOUSE · Apr 21, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a treatment called Gammaknife radiosurgery on patients with vestibular schwannomas, which are non-cancerous growths that can develop near the brainstem and affect balance and hearing. The trial aims to understand how this treatment influences balance and vestibular function—our body’s ability to maintain balance and spatial orientation—over time. While Gammaknife radiosurgery is known to stabilize these tumors in most cases with very low risks of damaging facial nerves, there is still some uncertainty about how well it preserves hearing and impacts balance. This study will gather information from patients using a quality of life questionnaire and other tests to get a clearer picture of these effects.

To be eligible for the trial, participants must be patients diagnosed with a vestibular schwannoma who have been recommended for Gammaknife radiosurgery and have not had any previous treatments for it. They should also be affiliated with Social Security and willing to participate in the study. However, individuals with a history of certain ear or balance-related conditions, those who have had prior treatments for their schwannoma, or pregnant or breastfeeding women cannot participate. Participants can expect to complete surveys and tests that will help researchers learn more about how Gammaknife treatment affects balance and overall quality of life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Vestibular schwannoma's Patients for whom an indication of gammaknife radiosurgery was determined in a dedicated multidisciplinary consultation meeting, having not received previous treatment for this schwannoma.
• • Patient affiliated to Social Security
• • No opposition to participation
• Exclusion Criteria:
• • History of prior treatment for the presented vestibular schwannoma (surgery, fractional radiotherapy)
• • History of otological or otoneurological pathology associated with schwannoma
• • Patient with type 2 neurofibromatosis
• • Patient under legal protection
• • Pregnant or breastfeeding women