SBRT in the Management of Solid Spinal Metastases

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Apr 23, 2021

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called Stereotactic Body Radiation Therapy (SBRT) for patients who have cancer that has spread to the spine and is causing pressure on the spinal cord. The goal is to see how effective SBRT is in managing these spinal metastases, which can lead to serious problems like pain or loss of movement. The trial is currently looking for participants who are adults aged 18 and older, have a confirmed diagnosis of spinal metastasis from a solid tumor, and may be facing surgery or only receiving SBRT if surgery isn’t possible.

Participants in this study will receive either surgery followed by SBRT or just SBRT alone, depending on their specific situation. Before joining, they must give their written consent, meaning they agree to take part in the study after understanding what it involves. It’s important to note that individuals with certain other health conditions or those who have received radiation treatment on the same spinal area previously may not be eligible. Overall, this trial aims to provide valuable information about how well SBRT can help manage spinal tumors and improve patients' quality of life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Radiological diagnosis of spinal metastasis from solid tumor with epidural imminent or actual spinal cord compression, with or without neurological deficits. Patients will be scheduled for surgery + SBRT. If contra-indications preclude surgery and only SBRT is performed, patients will still be included.
• • Written informed consent to participate in the study must be obtained from the subject or proxy /legal representative
• • Males and females \> 18 years
• Exclusion Criteria:
• • Any concomitant condition or disease which, in the opinion of the investigator, would affect the reliability of the collected data.
• • Patients that had previous radiotherapy on the index spinal level without the possibility for additional SBRT at that particular level.