DNA Adductomics for Colorectal Cancer Investigation
Launched by UNIVERSITY OF COPENHAGEN · Apr 28, 2021
Trial Information
Current as of July 24, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial, titled "DNA Adductomics for Colorectal Cancer Investigation," is looking to better understand colorectal cancer (CRC) by studying specific changes in DNA in colon tissue. The researchers are focusing on patients who have conditions like Familial Adenomatous Polyposis (FAP), Lynch syndrome, or other types of colorectal cancer. These patients will be undergoing surgery to remove part or all of their colon. The study will also include control patients who are having similar surgeries for other reasons. In addition to colon tissue, the trial will examine blood and urine samples to find DNA-related markers that could help in understanding how cancer develops.
To participate in this trial, individuals should be between 65 and 74 years old and have one of the specified conditions that require colon surgery. However, people who are under 18, those who have recently donated blood, or those who may not fully understand the study cannot take part. If eligible, participants can expect to provide tissue and fluid samples, which will help researchers learn more about colorectal cancer and how it might be prevented or treated in the future. This study is currently recruiting participants, and it aims to contribute valuable insights into the fight against colorectal cancer.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with either FAP, Lynch syndrome, other HNPCC, sporadic colorectal cancer, ulcerative colitis or other conditions who are scheduled for whole or partial resection of their colon
- Exclusion Criteria:
- • Any condition that makes the investigator or hospital personnel doubt that voluntary participation isfeasible.
- • Patients who are not able to understand and sign the informed consent form for any reason, including lack of a sufficient period of time to consider their participation.
- • Patients who are below 18 years of age.
- • Patients who donated blood to a blood bank within 3 months prior to their operation.
About University Of Copenhagen
The University of Copenhagen, a leading research institution in Denmark, is dedicated to advancing medical knowledge and improving patient outcomes through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university leverages its expertise in various fields, including health sciences, pharmacology, and biotechnology, to design and conduct rigorous clinical studies. Committed to ethical standards and scientific integrity, the University of Copenhagen aims to contribute significantly to the global medical community by facilitating groundbreaking research that addresses pressing healthcare challenges.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Copenhagen, Frederiksberg C, Denmark
Patients applied
Trial Officials
Lars Ove O Dragsted, PhD
Principal Investigator
University of Copenhagen
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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