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Search / Trial NCT04865809

Use of Ozonized Water With Toothpaste and Mousse in Non Surgical Periodontal Therapy for Patients With Diabetes Mellitus Type 1: a Randomized Clinical Trial.

Launched by UNIVERSITY OF PAVIA · Apr 26, 2021

Trial Information

Current as of August 02, 2025

Completed

Keywords

Ozonized Water Glycosylated Hemoglobin

ClinConnect Summary

The aim of this study is to evaluate the efficacy of Peribioma Toothpaste and Mousse for home oral care in patients with Diabetes Mellitus Type 1.

Patients who respond to eligibility criteria and that will sign the informed consent will undergo a professional oral hygiene procedure; then, ozonized water (aquolab) will be used to irrigate periodontal pockets for 1 minute.

Then, patients will be randomly divided into two groups:

* Trial Group: patients will use Biorepair Peribioma Toothpaste and Mousse for home oral care until the end of the study;
* Control Group: patients will use Biorep...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • patients suffering from Diabetes Mellitus Type 1
  • adult patients
  • patients who agreed to participate to the study and that signed the informed consent.
  • Exclusion Criteria:
  • patients taking intravenous or oral Bisphosphonates at the study begin or in the previous 12 months
  • patients with low compliance and motivation to participate
  • pazienti irradiati alla testa o collo negli ultimi 12 mesi
  • pregnant or breastfeeding women
  • alcohol and drug abuse
  • patients with psychiatric diseases

About University Of Pavia

The University of Pavia, a prestigious institution renowned for its commitment to academic excellence and research innovation, serves as a prominent clinical trial sponsor. With a strong emphasis on advancing medical knowledge and improving patient care, the university leverages its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous clinical research. Collaborating with leading healthcare professionals and institutions, the University of Pavia is dedicated to exploring novel therapeutic approaches and fostering the translation of scientific discoveries into clinical practice, ultimately aiming to enhance health outcomes and contribute to the global medical community.

Locations

Pavia, Lombardy, Italy

Patients applied

0 patients applied

Trial Officials

Andrea Scribante, DDS, PhD.

Principal Investigator

University of Pavia

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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