Posterior Segment Evaluation of Patients With SLE Using OCT and OCTA

Launched by MINIA UNIVERSITY · Apr 26, 2021

Keywords

ClinConnect Summary

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory

disease that involves different organs and systems. The heterogeneous nature of

the disease represents a great challenge in its diagnosis and management. Studies

reported that the percentage of SLE patients demonstrating ocular manifestations

can reach up to 30%.

The pathogenesis of the ocular involvement is still unclear, but immune

complex vasculopathy and inflammatory mediators might be implicated. The most

common ocular manifestation in SLE was found to be kerato-conjunctivitis

sicca(KCS) followed by retinop...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥18 years old.
• • 2. Patients with SLE diagnosed by a Rheumatologist with no ocular involvement upon clinical examination
• Exclusion Criteria:
• • 1. Patients with history of intraocular surgery as cataract surgery retinal detachment surgery and anti-glaucoma surgery.
• • 2. Patients with significant media opacity as corneal opacity, cataract.
• • 3. Patients with ocular diseases as glaucoma, uveitis.
• • 4. Patients with any retinal affection as pathological myopia, macular hole, age related macular degeneration and retinal vascular occlusion.
• • 5. Patients with systemic diseases as diabetes mellitus (DM), hypertension, abnormal kidney functions