The Impact of Cesarean Scar Defects on the Success of Assisted Human Reproduction

Launched by UNIVERSITY HOSPITAL, ANGERS · Apr 27, 2021

Keywords

ClinConnect Summary

This clinical trial is looking at how a type of scar defect called an isthmocele—an abnormal thinning or weakening of the uterus wall where a previous cesarean section was done—might affect the success of assisted reproductive treatments like IVF (in vitro fertilization). The study focuses on women who have had at least one cesarean delivery, are experiencing difficulty getting pregnant again (secondary infertility), and are planning to use fertility treatments. Doctors use a special ultrasound test called hysterosonography to spot these scar defects before treatment.

Women between 18 and 43 years old who speak French, have had a cesarean section, and are preparing for IVF or similar procedures may be eligible to join. Participants will undergo the usual fertility assessments, including the hysterosonography to check for scar defects, and their fertility treatment outcomes will be monitored. The goal is to understand whether these uterine scars affect the chances of getting pregnant with assisted reproduction. This information could help guide future treatment decisions, such as whether surgery to repair the scar might improve fertility outcomes.

Gender

FEMALE

Eligibility criteria

• Inclusion criteria :
• • Patients with a history of at least one cesarean section (single or multi-scarred uterus).
• • Age between 18 and 43 years old
• • Secondary infertility requiring ART techniques (FIV or FIV ICSI).
• • A Hysterosonography examination as part of the pre-ART assessment allowing for the detection of the presence of an isthmocele.
• • French speaking patients
• • Patient affiliated to or beneficiary of a social security scheme
• Non-inclusion criteria :
• • - Refusal to participate in the study.